Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomised, open-label, blinded-endpoint, controlled trial in a health-care setting.

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Abstract

Treatment guidelines for aphasia recommend intensive speech and language therapy for chronic (≥6 months) aphasia after stroke, but large-scale, class 1 randomised controlled trials on treatment effectiveness are scarce. We aimed to examine whether 3 weeks of intensive speech and language therapy under routine clinical conditions improved verbal communication in daily-life situations in people with chronic aphasia after stroke.

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Author and article information

Journal

Journal ID (iso-abbrev): Lancet

Title: Lancet (London, England)

Publisher: Elsevier BV

ISSN (Electronic): 1474-547X

ISSN (Print): 0140-6736

Publication date (Electronic): Apr 15 2017

Volume: 389

Issue: 10078

Affiliations

[1 ] Department of General Neurology (formerly Department of Neurology), University of Münster, Münster, Germany. Electronic address: caterina.breitenstein@uni-muenster.de.

[2 ] Faculty of Health and Social Sciences, Fresenius University of Applied Sciences, Idstein and Hamburg, Germany.

[3 ] NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany; Center for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany; Department of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany; Department of Neurology, University of Greifswald, Greifswald, Germany.

[4 ] Clinical Neuropsychology Research Group, Institute of Phonetics and Speech Processing, Ludwig-Maximilians-University, Munich, Germany.

[5 ] Clinical and Cognitive Neuroscience, Department of Neurology, University Hospital, RWTH Aachen University, Aachen, Germany.

[6 ] Institute for Clinical Epidemiology and Applied Biostatistics, University of Tübingen, Tübingen, Germany.

[7 ] Neuropsychology, Department of Neurology, University Hospital, RWTH Aachen University, Aachen, Germany.

[8 ] Department of General Neurology (formerly Department of Neurology), University of Münster, Münster, Germany.

[9 ] Center for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany; Department of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

[10 ] Neuropsychology, Department of Neurology, University Hospital, RWTH Aachen University, Aachen, Germany; School of Biological Sciences, University of Manchester, Manchester, UK.

[11 ] Neuropsychological Department, Bogenhausen Hospital, Munich, Germany.

[12 ] Institute of Germanic Linguistics, University of Marburg, Marburg, Germany.

[13 ] Clinic of Cognitive Neurology, University of Leipzig and Max Planck Institute for Cognitive and Brain Sciences, Leipzig, Germany.

[14 ] m&i Fachklinik Enzensberg, Fuessen, Germany.

[15 ] Reha-Centre Passauer Wolf, Bad Griesbach, Germany.

[16 ] NeuroCure Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany; Center for Stroke Research Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany; Department of Neurology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Article

Publisher Item ID: S0140-6736(17)30067-3

DOI: 10.1016/S0140-6736(17)30067-3

PubMed ID: 28256356

SO-VID: 73432478-c1fe-4018-a5d4-294e2589550b

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