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      Valvular heart disease in pregnancy

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      , MB ChB, FCOG, MPhil,, , MB ChB, FCOG, MMed, , MB BS, FWACP
      Cardiovascular Journal of Africa
      Clinics Cardive Publishing
      valvular, heart disease, pregnancy

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          Abstract

          Valvular heart disease may be a pre-existing complication of pregnancy or it may be diagnosed for the first time during pregnancy. Accurate diagnosis, tailored therapy and an understanding of the physiology and pathophysiology of pregnancy are necessary components of management, best achieved through the use of multidisciplinary clinics. This review outlines the management of specific lesions, with particular reference to post-rheumatic valvular heart disease.

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          Most cited references41

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          ESC Guidelines for the management of grown-up congenital heart disease (new version 2010).

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            Rheumatic heart disease

            Rheumatic heart disease, often neglected by media and policy makers, is a major burden in developing countries where it causes most of the cardiovascular morbidity and mortality in young people, leading to about 250,000 deaths per year worldwide. The disease results from an abnormal autoimmune response to a group A streptococcal infection in a genetically susceptible host. Acute rheumatic fever--the precursor to rheumatic heart disease--can affect different organs and lead to irreversible valve damage and heart failure. Although penicillin is effective in the prevention of the disease, treatment of advanced stages uses up a vast amount of resources, which makes disease management especially challenging in emerging nations. Guidelines have therefore emphasised antibiotic prophylaxis against recurrent episodes of acute rheumatic fever, which seems feasible and cost effective. Early detection and targeted treatment might be possible if populations at risk for rheumatic heart disease in endemic areas are screened. In this setting, active surveillance with echocardiography-based screening might become very important. Copyright © 2012 Elsevier Ltd. All rights reserved.
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              Trends in infective endocarditis incidence, microbiology, and valve replacement in the United States from 2000 to 2011.

              In accordance with the 2007 American College of Cardiology and American Heart Association infective endocarditis (IE) guideline update, antibiotic prophylaxis is now being restricted to a smaller number of cardiac conditions with very high risk for adverse outcomes from IE. However, there is scant data on IE trends since this major practice change in the United States.
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                Author and article information

                Contributors
                Journal
                Cardiovasc J Afr
                Cardiovasc J Afr
                TBC
                Cardiovascular Journal of Africa
                Clinics Cardive Publishing
                1995-1892
                1680-0745
                Mar-Apr 2016
                : 27
                : 2
                : 111-118
                Affiliations
                Division of Obstetrics and Gynaecology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa
                Division of Obstetrics and Gynaecology, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa
                Department of Medicine, Bayero University Kano and Aminu Kano Teaching Hospital, Kanu, Nigeria
                Article
                10.5830/CVJA-2016-052
                4928166
                27213859
                716fb80a-427e-4db2-9ad8-ee56d0616113
                Copyright © 2015 Clinics Cardive Publishing

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 9 February 2016
                : 14 April 2016
                Categories
                Cardiovascular Topics

                valvular,heart disease,pregnancy
                valvular, heart disease, pregnancy

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