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      The Development, Application and Analysis of an Enhanced Recovery Programme for Major Oesophagogastric Resection

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          Abstract

          Background

          Enhanced recovery programmes improve outcomes in surgery, but their implementation after upper gastrointestinal resection has been limited. The aim of this study was to compare short-term outcomes for patients undergoing oesophagogastric surgery in an enhanced recovery programme (EROS).

          Methods

          EROS was developed after a multidisciplinary meeting by multiple rounds of revision. EROS was applied to all patients undergoing major upper GI resection at a university teaching hospital in the UK from 20/9/13, with data reviewed at 18/09/15. EROS was assessed to identify predictors for compliance.

          Results

          One hundred six patients underwent major upper GI resection including 81 oesophagectomies, 24 gastrectomies and 1 colonic interposition graft. Major complications (Clavien Dindo ≥3) occurred in 12 patients with 1 in-hospital death. Thirty-five patients (44%) were discharged on target day 8 of the EROS programme. Age and complications were independently associated with missing this discharge target.

          Conclusion

          Enhanced recovery is feasible and safe after major upper gastrointestinal surgery.

          Electronic supplementary material

          The online version of this article (doi:10.1007/s11605-017-3363-8) contains supplementary material, which is available to authorized users.

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          Most cited references15

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          A protocol is not enough to implement an enhanced recovery programme for colorectal resection.

          Single-centre studies have suggested that enhanced recovery can be achieved with multimodal perioperative care protocols. This international observational study evaluated the implementation of an enhanced recovery programme in five European centres and examined the determinants affecting recovery and length of hospital stay. Four hundred and twenty-five consecutive patients undergoing elective open colorectal resection above the peritoneal reflection between January 2001 and January 2004 were enrolled in a protocol that defined multiple perioperative care elements. One centre had been developing multimodal perioperative care for 10 years, whereas the other four had previously undertaken traditional care. The case mix was similar between centres. Protocol compliance before and during the surgical procedure was high, but it was low in the immediate postoperative phase. Patients fulfilled predetermined recovery criteria a median of 3 days after operation but were actually discharged a median of 5 days after surgery. Delay in discharge and the development of major complications prolonged length of stay. Previous experience with fast-track surgery was associated with a shorter hospital stay. Functional recovery in 3 days after colorectal resection could be achieved in daily practice. A protocol is not enough to enable discharge of patients on the day of functional recovery; more experience and better organization of care may be required. Copyright (c) 2006 British Journal of Surgery Society Ltd.
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            Enhanced recovery for esophagectomy: a systematic review and evidence-based guidelines.

            This article aims to provide the first systematic review of enhanced recovery after surgery (ERAS) programs for esophagectomy and generate guidelines.
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              Cost-benefit analysis of an enhanced recovery protocol for pancreaticoduodenectomy

              Enhanced recovery after surgery (ERAS) programmes have been shown to decrease complications and hospital stay. The cost-effectiveness of such programmes has been demonstrated for colorectal surgery. This study aimed to assess the economic outcomes of a standard ERAS programme for pancreaticoduodenectomy.
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                Author and article information

                Contributors
                tju@soton.ac.uk
                james.byrne@uhs.nhs.uk
                Journal
                J Gastrointest Surg
                J. Gastrointest. Surg
                Journal of Gastrointestinal Surgery
                Springer US (New York )
                1091-255X
                1873-4626
                24 January 2017
                24 January 2017
                2017
                : 21
                : 4
                : 614-621
                Affiliations
                [1 ]ISNI 0000000103590315, GRID grid.123047.3, Department of Surgery, , University Hospital Southampton, ; Tremona Road, Southampton, Hampshire SO16 6YD UK
                [2 ]Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Somers Cancer Research Building, MP824, Southampton General Hospital, Southampton, Hampshire SO16 6YD UK
                Article
                3363
                10.1007/s11605-017-3363-8
                5359364
                28120276
                71644149-f3f1-4219-926f-09ad2c5d6ec5
                © The Author(s) 2017

                Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

                History
                : 29 September 2016
                : 4 January 2017
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100000265, Medical Research Council;
                Award ID: G1002565
                Award Recipient :
                Categories
                Original Article
                Custom metadata
                © The Society for Surgery of the Alimentary Tract 2017

                Surgery
                enhanced recovery,oesophageal surgery,surgery,oesophagectomy,gastrectomy
                Surgery
                enhanced recovery, oesophageal surgery, surgery, oesophagectomy, gastrectomy

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