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Abstract
<p class="first" id="d26018355e69">Endometrial receptivity is a complex process that
provides the embryo with the opportunity
to attach, invade, and develop, culminating in a new individual and continuation of
the species. The window of implantation extends 3-6 days within the secretory phase
in most normal women. In certain inflammatory or anatomic conditions, this window
is narrowed or shifted to preclude normal implantation, leading to infertility or
pregnancy loss. Of the factors that prevent normal implantation and pregnancy, embryo
and endometrial quality share responsibility. In this review, we highlight the advances
in the study of implantation from the perspective of the endometrium, normally a barrier
to implantation. New advances will allow the early identification of defects in endometrial
receptivity and provide new avenues for treatment that promote successful establishment
of pregnancy.
</p>