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Successful treatment of disseminated granuloma annulare with adalimumab.

Author(s): Scott Schlauder, Barbara Laraia, Alice B Gottlieb, David Rosmarin

Publication date: 2009-01-31

Journal: Journal of drugs in dermatology : JDD

Keywords: Anti-Inflammatory Agents, therapeutic use, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Biopsy, Female, Granuloma Annulare, drug therapy, immunology, pathology, Histiocytes, ultrastructure, Humans, Middle Aged, Treatment Outcome, Tumor Necrosis Factor-alpha, antagonists & inhibitors

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Abstract

A 61-year-old female with a 4-year history of disseminated granuloma annulare was successfully treated with the antitumor necrosis factor (TNF)-alpha antibody, adalimumab. The patient had failed high potency topical glucocorticoids, hydroxychloroquine, and narrow-band ultraviolet light (UV)-B phototherapy. Anti-TNF-alpha therapy may be a therapeutic option in patients with disseminated granuloma annulare poorly controlled with conventional medications.

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PubMed ID:: 19213233

ScienceOpen disciplines: Chemistry

Keywords: Anti-Inflammatory Agents,therapeutic use,Antibodies, Monoclonal,Antibodies, Monoclonal, Humanized,Biopsy,Female,Granuloma Annulare,drug therapy,immunology,pathology,Histiocytes,ultrastructure,Humans,Middle Aged,Treatment Outcome,Tumor Necrosis Factor-alpha,antagonists & inhibitors

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ScienceOpen disciplines: Chemistry

Successful treatment of disseminated granuloma annulare with adalimumab.

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