Effectiveness of the Medical Chatbot PROSCA to Inform Patients About Prostate Cancer: Results of a Randomized Controlled Trial

Take Home Message

The randomized controlled trial highlights that the chatbot PROSCA (PROState cancer Conversational Agent) effectively reduced the information needs of patients facing prostate cancer diagnosis compared with the standard education. High levels of user satisfaction demonstrate the potential for integrating evidence-based chatbots into health care.

Abstract

Background and objective

Artificial intelligence (AI)-powered conversational agents are increasingly finding application in health care, as these can provide patient education at any time. However, their effectiveness in medical settings remains largely unexplored. This study aimed to assess the impact of the chatbot “PROState cancer Conversational Agent” (PROSCA), which was trained to provide validated support from diagnostic tests to treatment options for men facing prostate cancer (PC) diagnosis.

Methods

The chatbot PROSCA, developed by urologists at Heidelberg University Hospital and SAP SE, was evaluated through a randomized controlled trial (RCT). Patients were assigned to either the chatbot group, receiving additional access to PROSCA alongside standard information by urologists, or the control group (1:1), receiving standard information. A total of 112 men were included, of whom 103 gave feedback at study completion.

Key findings and limitations

Over time, patients’ information needs decreased significantly more in the chatbot group than in the control group ( p = 0.035). In the chatbot group, 43/54 men (79.6%) used PROSCA, and all of them found it easy to use. Of the men, 71.4% agreed that the chatbot improved their informedness about PC and 90.7% would like to use PROSCA again. Limitations are study sample size, single-center design, and specific clinical application.

Conclusions and clinical implications

With the introduction of the PROSCA chatbot, we created and evaluated an innovative, evidence-based AI health information tool as an additional source of information for PC. Our RCT results showed significant benefits of the chatbot in reducing patients’ information needs and enhancing their understanding of PC. This easy-to-use AI tool provides accurate, timely, and accessible support, demonstrating its value in the PC diagnosis process. Future steps include further customization of the chatbot’s responses and integration with the existing health care systems to maximize its impact on patient outcomes.

Patient summary

This study evaluated an artificial intelligence–powered chatbot—PROSCA, a digital tool designed to support men facing prostate cancer diagnosis by providing validated information from diagnosis to treatment. Results showed that patients who used the chatbot as an additional tool felt better informed than those who received standard information from urologists. The majority of users appreciated the ease of use of the chatbot and expressed a desire to use it again; this suggests that PROSCA could be a valuable resource to improve patient understanding in prostate cancer diagnosis.