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Structural and molecular basis of the role of starch and sucrose in Streptococcus mutans biofilm development.

Author(s): Marlise Klein, S Mitra, J. Xiao, Jeffrey Foster, Marcio Duarte, Edward Koo

Publication date: 2009-01-31

Journal: Applied and Environmental Microbiology

Keywords: Amylases, metabolism, Biofilms, growth & development, Glucosyltransferases, Humans, Protein Binding, Saliva, enzymology, Starch, Streptococcus mutans, Sucrose

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Abstract

The interaction of sucrose and starch with bacterial glucosyltransferases and human salivary amylase may enhance the pathogenic potential of Streptococcus mutans within biofilms by influencing the structural organization of the extracellular matrix and modulating the expression of genes involved in exopolysaccharide synthesis and specific sugar transport and two-component systems.

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PubMed ID:: 19028906

PMC ID:: 2632160

DOI:: 10.1128/AEM.01299-08

ScienceOpen disciplines: Chemistry

Keywords: Amylases,metabolism,Biofilms,growth & development,Glucosyltransferases,Humans,Protein Binding,Saliva,enzymology,Starch,Streptococcus mutans,Sucrose

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ScienceOpen disciplines: Chemistry

Keywords: Amylases, metabolism, Biofilms, growth & development, Glucosyltransferases, Humans, Protein Binding, Saliva, enzymology, Starch, Streptococcus mutans, Sucrose

Structural and molecular basis of the role of starch and sucrose in Streptococcus mutans biofilm development.

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