Changes in fetoplacental Doppler indices following intrapartum maternal sildenafil citrate treatment.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Uterine contractions during labour can result in a 60 % decline in fetoplacental perfusion, predisposing the fetus to hypoxic brain injury. Sildenafil citrate (SC) has shown promise in increasing uteroplacental perfusion as well as reducing the risk of operative birth for intrapartum fetal compromise (IFC). The aim of this study was to investigate the effect of intrapartum SC administration on fetoplacental blood flow indices.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Eur J Obstet Gynecol Reprod Biol

Title: European journal of obstetrics, gynecology, and reproductive biology

Publisher: Elsevier BV

ISSN (Electronic): 1872-7654

ISSN (Print): 0301-2115

Publication date (Electronic): Nov 2020

Volume: 254

Affiliations

[1 ] Mater Research Institute, University of Queensland, Level 3 Aubigny Place, Raymond Terrace, South Brisbane, Queensland, 4101, Australia; Faculty of Medicine, University of Queensland, Whitty Building, Annerley Road, South Brisbane, Queensland, 4101, Australia.

[2 ] Mater Research Institute, University of Queensland, Level 3 Aubigny Place, Raymond Terrace, South Brisbane, Queensland, 4101, Australia.

[3 ] Mater Research Institute, University of Queensland, Level 3 Aubigny Place, Raymond Terrace, South Brisbane, Queensland, 4101, Australia; Faculty of Medicine, University of Queensland, Whitty Building, Annerley Road, South Brisbane, Queensland, 4101, Australia. Electronic address: sailesh.kumar@mater.uq.edu.au.

Article

Publisher Item ID: S0301-2115(20)30620-5

DOI: 10.1016/j.ejogrb.2020.09.042

PubMed ID: 33045501

SO-VID: 6f07fd37-9d71-4914-821c-3e45060f5191

History

Keywords: Intrapartum fetal compromise,Middle cerebral artery,Sildenafil citrate,Ultrasound doppler indices,Umbilical artery,Uterine artery,Uteroplacental perfusion,Fetal distress,Fetus,Labour

Data availability:

Keywords: Intrapartum fetal compromise, Middle cerebral artery, Sildenafil citrate, Ultrasound doppler indices, Umbilical artery, Uterine artery, Uteroplacental perfusion, Fetal distress, Fetus, Labour

Changes in fetoplacental Doppler indices following intrapartum maternal sildenafil citrate treatment.

Read this article at

Abstract

Related collections

Advocacy for Maternal and Women’s Health

Author and article information

Journal

Affiliations

Article

History

Comments

Comment on this article

Similar content 68

Cited by 2