Novel Chinese Angelica Polysaccharide Biomimetic Nanomedicine to Curcumin Delivery for Hepatocellular Carcinoma Treatment and Immunomodulatory Effect

Guo, Chunjing; Hou, Xiaoya; Liu, Yanhui; Zhang, Yanchun; Xu, Haiyu; Zhao, Feng H.; Chen, Daquan

doi:10.1016/j.phymed.2020.153356

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Novel Chinese Angelica Polysaccharide Biomimetic Nanomedicine to Curcumin Delivery for Hepatocellular Carcinoma Treatment and Immunomodulatory Effect

Author(s): Chunjing Guo , Xiaoya Hou , Yanhui Liu , Yanchun Zhang , Haiyu Xu , Feng Zhao , Daquan Chen

Publication date Created: January 2021

Publication date (Print): January 2021

Journal: Phytomedicine

Publisher: Elsevier BV

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Most cited references 48

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Hepatocellular carcinoma.

Hashem El-Serag (2011)

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Polysaccharides-based nanoparticles as drug delivery systems.

Zonghua Liu, Yanpeng Jiao, Yifei Wang … (2008)

Natural polysaccharides, due to their outstanding merits, have received more and more attention in the field of drug delivery systems. In particular, polysaccharides seem to be the most promising materials in the preparation of nanometeric carriers. This review relates to the newest developments in the preparation of polysaccharides-based nanoparticles. In this review, four mechanisms are introduced to prepare polysaccharides-based nanoparticles, that is, covalent crosslinking, ionic crosslinking, polyelectrolyte complex, and the self-assembly of hydrophobically modified polysaccharides.