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Volume change in amygdala enlargement as a prognostic factor in patients with temporal lobe epilepsy: A longitudinal study.
Han Kyu Na
1 ,
Ho-Joon Lee
2 ,
Seok-Jun Hong
3 ,
Dong Hyun Lee
1 ,
Kyung Min Kim
1 ,
Hyung Woo Lee
1 ,
Kyoung Heo
1 ,
Kyoo Ho Cho
1
January 2020
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Abstract
Considering the clinical heterogeneity of temporal lobe epilepsy with amygdala enlargement (TLE-AE), identifying distinct prognostic subgroups of TLE-AE has clinical implications. Until now, baseline volume of the enlarged amygdala (EAV) has consistently failed to predict prognosis in TLE-AE. Based on studies suggesting that patients responsive to antiepileptic drugs (AEDs) exhibit remission of AE on follow-up imaging, we investigated whether reduction rate of EAV is predictive of long-term prognosis in TLE-AE.