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      Albendazole is effective in controlling monogeneans in Colossoma macropomum (Serrasalmidae): therapeutic baths and their physiological and histopathological effects Translated title: Albendazol tem eficácia em controlar monogenéticos em Colossoma macropomum (Serrasalmidae): banhos terapêuticos e seus efeitos fisiológicos e histopatológicos

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          Abstract

          In aquaculture worldwide, most of the chemotherapeutic agents used for disease control and treatment are unregulated chemical products derived from agriculture. In this study, we investigated the efficacy of therapeutic baths with albendazole against the monogeneans Anacanthorus spathulatus, Notozothecium janauachensis and Mymarothecium boegeri, which infest the gills of Colossoma macropomum, and the hematological and histopathological effects of this anthelmintic agent on these fish. Albendazole at a concentration of 500 mg/L was used in three baths of 24 hours each, with intervals of 24 hours between these baths. Three replications of this treatment were used, and the control group consisted of water from the cultivation tank. Afterwards, hematological, histopathological and parasitological analyses were conducted. We found that the therapeutic baths with albendazole at 500 mg/L presented high efficacy (94.9%) against monogeneans de C. macropomum and caused few physiological or histopathological alterations. Therefore, baths with albendazole at 500 mg/L, as used in this strategy, can be recommended for controlling and treating infections by monogeneans in C. macropomum.

          Resumo

          Na aquicultura mundial, a maioria dos quimioterápicos utilizados no controle e tratamento de doenças, são produtos químicos não regulamentados e oriundos da agricultura. Neste estudo, foi investigada a eficácia de banhos terapêuticos com albendazol contra monogeneas Anacanthorus spathulatus, Notozothecium janauachensis e Mymarothecium boegeri das brânquias de Colossoma macropomum, e os efeitos hematológicos e histopatológicos causados por esse anti-helmíntico nos peixes. Foram usados 500 mg/L de albendazol e um grupo controle (água do tanque de cultivo) com três banhos de 24 horas, mantendo intervalos de 24 horas entre cada banho, usando três repetições cada. Ao final dos banhos terapêuticos, foram realizadas análises hematológicas, histopatológicas e parasitológicas. Verificou-se que banhos terapêuticos com 500 mg/L de albendazol apresentaram alta eficácia (94,9%) contra monogenéticos de C. macropomum, causando poucas alterações fisiológicas e histopatológicas. Portanto, banhos com 500 mg/L de albendazol, na estratégia usada, podem ser recomendados para controle e tratamento de infecções por monogenéticos em C. macropomum.

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                Author and article information

                Journal
                Rev Bras Parasitol Vet
                Rev Bras Parasitol Vet
                rbpv
                Revista Brasileira de Parasitologia Veterinária / Brazilian Journal of Veterinary Parasitology
                Colégio Brasileiro de Parasitologia Veterinária
                0103-846X
                1984-2961
                26 August 2024
                2024
                : 33
                : 3
                : e004924
                Affiliations
                [1 ] originalPrograma de Pós-graduação em Biodiversidade Tropical – PPGBIO, Universidade Federal do Amapá – UNIFAP, Macapá, AP, Brasil
                [2 ] originalLaboratório de Morfofisiologia e Sanidade Animal, Universidade do Estado do Amapá – UEAP, Macapá, AP, Brasil
                [3 ] originalEmbrapa Amapá, Macapá, AP, Brasil
                Author notes
                [* ]Corresponding author: Raimundo Rosemiro de Jesus Baia. E-mail: rdobaia@ 123456gmail.com

                Conflict of interest :The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

                Author information
                http://orcid.org/0000-0001-9760-7324
                Article
                rbpvAO04924_EN 00402
                10.1590/S1984-29612024044
                11452061
                39194144
                6d866596-4777-4958-840d-db75676ebd0c

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 05 March 2024
                : 06 June 2024
                Page count
                Figures: 1, Tables: 3, Equations: 0, References: 36
                Funding
                Funded by: CNPQ
                Award ID: 301911/2022-3
                Categories
                Original Article

                anthelmintic,parasites,tambaqui,treatment,anti-helmíntico,parasitos,tratamento

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