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      Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial.

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          Abstract

          In multiple myeloma, combination chemotherapy with melphalan plus prednisone is still regarded as the standard of care in elderly patients. We assessed whether the addition of thalidomide to this combination, or reduced-intensity stem cell transplantation, would improve survival.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          1474-547X
          0140-6736
          Oct 06 2007
          : 370
          : 9594
          Affiliations
          [1 ] Service d'Hématologie, Centre Hospitalier Universitaire, Lille, France. t-facon@chru-lille.fr
          Article
          S0140-6736(07)61537-2
          10.1016/S0140-6736(07)61537-2
          17920916
          6d3e55f5-cce2-4ce0-9b76-bb2d1a76473f
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