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Pharmacokinetics of intraperitoneal cefazolin and ceftazidime coadministered to CAPD patients.
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Abstract
Guidelines for empiric treatment of PD-related peritonitis published in 2000 recommend concurrent intraperitoneal (IP) cefazolin and ceftazidime. The pharmacokinetics (PK) of these agents combined have not been studied. This study was designed to determine the PK of combined IP cefazolin and ceftazidime in CAPD patients.