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      IRONMAN adds support for iron repletion in HF

      brief-report
      Nature Reviews. Cardiology
      Nature Publishing Group UK
      Heart failure, Therapeutics

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          Abstract

          The IRONMAN trial adds further support to the known benefits of intravenous iron therapy in patients with heart failure (HF) with reduced ejection fraction and iron deficiency, but narrowly misses the primary end point of hospitalization for HF and cardiovascular death.

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          Is Open Access

          Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial

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            Author and article information

            Contributors
            nrcardio@nature.com
            Journal
            Nat Rev Cardiol
            Nat Rev Cardiol
            Nature Reviews. Cardiology
            Nature Publishing Group UK (London )
            1759-5002
            1759-5010
            21 November 2022
            : 1
            Affiliations
            Nature Reviews Cardiology, http://www.nature.com/nrcardio/
            Article
            815
            10.1038/s41569-022-00815-5
            9684863
            36414679
            6d08685a-e468-4036-ae3c-5420dba83a51
            © Springer Nature Limited 2022

            This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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            Research Highlight

            heart failure,therapeutics
            heart failure, therapeutics

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