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      • Record: found
      • Abstract: found
      • Article: found

      Autologous Non-Cultured Epidermal Cellular Grafting in the Surgical Treatment of Stable Vitiligo: The Skin Hospital Protocol

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          Abstract

          Autologous non-cultured epidermal cellular grafting is the treatment of choice for patients with stable refractory vitiligo. Recently, studies have shown cost-effective alternatives for this procedure, superseding previous techniques that required large research facilities or expensive pre-packaged kits. We provide modifications to current techniques, including the use of individual Petri dishes to allow for processing larger skin grafts, hyfrecation instead of conventional manual dermabrasion of the recipient site to reduce scar formation as well as better margin delineation, and an intravenous giving set with a filter for improved filtration of the mixed cell population. These modifications facilitated sufficient skin repigmentation in a cost-effective outpatient setting.

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          Six-year follow-up of vitiligo patients successfully treated with autologous non-cultured melanocyte-keratinocyte transplantation.

          S Altalhab, M I AlJasser, S V Mulekar … (2019)
          Although autologous non-cultured melanocyte-keratinocyte transplantation is a treatment option for stable vitiligo, there is lack of long-term maintenance data for this specific treatment.
          Article 0 comments Cited 8 times – based on 0 reviews     Review now
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            Four compartment method as an efficacious and simplified technique for autologous non-cultured epidermal cell suspension preparation in vitiligo surgery: A randomized, active-controlled study.

            S Mrigpuri, M Razmi T, M Sendhil Kumaran … (2019)
            Autologous non-cultured epidermal cell suspension (NCES) is a successful surgical method for repigmentation of stable, refractory vitiligo. The need for laboratory equipment and expertise restricts its use to only a few research centres; hence, there is a requisite to simplify the technique of NCES preparation.
            Article 0 comments Cited 4 times – based on 0 reviews     Review now
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              Four compartment method: a simplified and cost-effective method of noncultured epidermal cell suspension for the treatment of vitiligo.

              R. Kumar, D Parsad, C Singh … (2014)
              Despite continued progress towards an elucidation of pathogenetic pathways in vitiligo, a definitive cure remains elusive. Noncultured epidermal cell suspension (NCECS) is emerging as the treatment of choice for surgical management of both stable and segmental vitiligo. NCECS is very effective in repigmenting stable vitiligo, but the technique requires an expert and the support of a laboratory facility.
              Article 0 comments Cited 4 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (publisher-id): DRM
                Journal ID (nlm-ta): Dermatology
                Journal ID (doi): 10.1159/issn.1018-8665
                Title: Dermatology
                Publisher: S. Karger AG
                ISSN (Print): 1018-8665
                ISSN (Electronic): 1421-9832
                Publication date Subscription-year: 2022
                Publication date (Print): January 2022
                Publication date (Electronic): 23 April 2021
                Volume: 238
                Issue: 1
                Pages: 167-169
                Affiliations
                [_a] aThe Skin Hospital, Sydney, New South Wales, Australia
                [_b] bFaculty of Medicine, University of New South Wales, Western Sydney University, Sydney, New South Wales, Australia
                Author information
                https://orcid.org/0000-0002-9497-0504
                Article
                Publisher ID: 515084 Other ID: Dermatology 2022;238:167–169
                DOI: 10.1159/000515084
                PubMed ID: 33895742
                SO-VID: 6cc03e22-265d-42e6-98da-4fc94505b928
                Copyright © © 2021 S. Karger AG, Basel
                License:

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                History
                Date received : 30 December 2020
                Date accepted : 06 February 2021
                Page count
                Figures: 2, Pages: 3
                Categories
                Subject: Surgical Pearls

                ScienceOpen disciplines: Oncology & Radiotherapy,Pathology,Surgery,Dermatology,Pharmacology & Pharmaceutical medicine
                Keywords: Treatment,Vitiligo,Surgical techniques,Autologous transplantation,Dermatologic surgery
                Data availability:
                ScienceOpen disciplines: Oncology & Radiotherapy, Pathology, Surgery, Dermatology, Pharmacology & Pharmaceutical medicine
                Keywords: Treatment, Vitiligo, Surgical techniques, Autologous transplantation, Dermatologic surgery

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