9
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      [32P-incorporation in adenosine phosphates of the rat brain after oral application of vincamine for 2 weeks (author's transl)].

      Arzneimittel-Forschung
      Adenine Nucleotides, metabolism, Adenosine Diphosphate, Adenosine Monophosphate, Adenosine Triphosphate, Animals, Brain, drug effects, Female, Phosphorus Radioisotopes, diagnostic use, Rats, Vinca Alkaloids, pharmacology, Vincamine

      Read this article at

      ScienceOpenPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The 32P-incorporation into the adenosine phosphates AMP, ADP and ATP of the rat brain after an oral administration of a daily dose of 20 mg/kg 14,15-dihydro14 beta-hydroxy-(3 alpha,16 alpha)-eburnamenine-14-carbonic acid methylester (vincamine; Vincapront) during two weeks was determined. The concentrations of the three adenosine phosphates did not change. After the administration of vincamine the increase in the 32P-incorporation into AMP and ADP was statistically significant. The results obtained are discussed in regard to an acceleration of the pentose phosphate shunt and an activation of adenylate kinase.

          Related collections

          Author and article information

          Comments

          Comment on this article