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      Effect of dried fruits of Carica papaya Linn on hepatotoxicity.

      Biological & pharmaceutical bulletin
      Animals, Carbon Tetrachloride, toxicity, Carica, Food Preservation, Fruit, Lethal Dose 50, Liver, drug effects, metabolism, pathology, Male, Plant Extracts, isolation & purification, pharmacology, Rats

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          Abstract

          Ethanol and aqueous extracts of Carica papaya has been evaluated for its anti hepatotoxic activity. The ethanol and aqueous extracts of Carica papaya showed remarkable hepatoprotective activity against CCl(4) induced hepatotoxicity. The activity was evaluated by using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase, total bilirubin and gamma glutamate transpeptidase (GGTP). The histopathological changes of liver sample was compared with respect to control.

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