Prognostic value and clinicopathological status of PD-L1 expression and CD8+ TILs in oral squamous cell cancer patients with or without traditional risk factors.

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Abstract

Non-smokers, non-drinkers, and non-betel quid chewers (NSNDNBs) with oral squamous cell carcinoma (OSCC) have poor survival outcomes. Tumor microenvironment based on PD-L1/CD8+ T cell infiltrated lymphocyte (TIL) proportion is proposed as a prognostic indicator.

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Author and article information

Journal

Journal ID (iso-abbrev): Head Neck

Title: Head & neck

Publisher: Wiley

ISSN (Electronic): 1097-0347

ISSN (Print): 1043-3074

Publication date (Electronic): Apr 2023

Volume: 45

Issue: 4

Affiliations

[1 ] Department of Otorhinolaryngology, Chulabhorn Hospital, Bangkok, Thailand.

[2 ] Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

[3 ] Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Article

DOI: 10.1002/hed.27330

PubMed ID: 36811208

SO-VID: 6a9b63d4-a17c-4d72-8b3e-ad64487d4384

History

Keywords: non-smoker,smoker and/or drinker and/or betel quid chewer,oral squamous cell cancer,non-drinker,non-betel quid chewer,PD-L1,CD8 tumor-infiltrating lymphocytes

Data availability:

Keywords: non-smoker, smoker and/or drinker and/or betel quid chewer, oral squamous cell cancer, non-drinker, non-betel quid chewer, PD-L1, CD8 tumor-infiltrating lymphocytes

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