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      Topical pine tar: History, properties and use as a treatment for common skin conditions

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          Abstract

          Pine tar is the end product of pine wood carbonisation following distillation using extreme heat. An extensive literature search was conducted back to the 1950s for this review. Pine tar has been used in medicine for more than 2000 years to treat a range of skin conditions because of its soothing and antiseptic properties. Pine tar should not be confused with coal tar, which has been produced from coal for approximately a hundred years. Pine tar is thought to exert its effect by reducing DNA synthesis and mitotic activity, which promotes a return to normal keratinisation. In addition, pine tar has been shown to be antipruritic, anti‐inflammatory, antibacterial and antifungal. These properties make pine tar suitable for the topical treatment of eczema, psoriasis, seborrhoeic dermatitis and other dry, itchy, flaky or inflamed skin conditions. Topical products available over‐the‐counter in Australia today contain up to 2.3% pine tar, and come in several different formulations that can be used on the entire body, including the face. Modern day pine tar is manufactured with increased purity to eliminate toxic phenol and carcinogenic components, which have been of concern in the past. Primary irritation is uncommon. In conclusion, the long experience with topical pine tar therapy and its worldwide usage, together with the evidence presented in this review, suggests that pine tar is an effective treatment with minimal safety risk.

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          Most cited references53

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          Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.

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            Topical tar: back to the future.

            The use of medicinal tar for dermatologic disorders dates back to the ancient times. Although coal tar is utilized more frequently in modern dermatology, wood tars have also been widely employed. Tar is used mainly in the treatment of chronic stable plaque psoriasis, scalp psoriasis, atopic dermatitis, and seborrheic dermatitis, either alone or in combination therapy with other medications, phototherapy, or both. Many modifications have been made to tar preparations to increase their acceptability, as some dislike its odor, messy application, and staining of clothing. One should consider a tried and true treatment with tar that has led to clearing of lesions and prolonged remission times. Occupational studies have demonstrated the carcinogenicity of tar; however, epidemiologic studies do not confirm similar outcomes when used topically. This article will review the pharmacology, formulations, efficacy, and adverse effects of crude coal tar and other tars in the treatment of selected dermatologic conditions.
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              Contact dermatitis in children.

              168 children, 14 years of age or younger, were patch tested with the Standard Series of the International Contact Dermatitis Research Group (ICDRG) over a 5-year period. 77 of the children had 1 or more positive reactions; relevant test results were found in 80% of them. 8 boys and 24 girls were allergic to nickel, which proved to be the most common allergen; 5 boys and 6 girls reacted to chromate, and 5 boys and 4 girls reacted to one or more of the rubber chemicals.
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                Author and article information

                Contributors
                kerryng@egopharm.com
                Journal
                Australas J Dermatol
                Australas. J. Dermatol
                10.1111/(ISSN)1440-0960
                AJD
                The Australasian Journal of Dermatology
                John Wiley and Sons Inc. (Hoboken )
                0004-8380
                1440-0960
                20 January 2016
                May 2017
                : 58
                : 2 ( doiID: 10.1111/ajd.2017.58.issue-2 )
                : 80-85
                Affiliations
                [ 1 ]Ego Pharmaceuticals Braeside VictoriaAustralia
                Author notes
                [*] [* ]Correspondence: Dr Kerryn A Greive, Ego Pharmaceuticals Pty Ltd, 21‐31 Malcolm Road, Braeside, Vic. 3195, Australia. Email: kerryng@ 123456egopharm.com
                Article
                AJD12427
                10.1111/ajd.12427
                5434829
                26790564
                6a5f763d-2a4c-4ede-872c-abfab6a4e137
                © 2016 The Authors. Australasian Journal of Dermatology © 2016 The Australasian College of Dermatologists.

                This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 03 September 2015
                : 25 October 2015
                Page count
                Figures: 0, Tables: 2, Pages: 6, Words: 5421
                Categories
                Review Article
                Review Articles
                Custom metadata
                2.0
                ajd12427
                May 2017
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.0.9 mode:remove_FC converted:17.05.2017

                coal tar,eczema,pine tar,psoriasis,seborrhoeic dermatitis
                coal tar, eczema, pine tar, psoriasis, seborrhoeic dermatitis

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