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Cellular functions of long noncoding RNAs
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Abstract
<p class="first" id="d16221063e87">A diverse catalog of long noncoding RNAs (lncRNAs),
which lack protein-coding potential,
are transcribed from the mammalian genome. They are emerging as important regulators
in gene expression networks by controlling nuclear architecture and transcription
in the nucleus and by modulating mRNA stability, translation and post-translational
modifications in the cytoplasm. In this Review, we highlight recent progress in cellular
functions of lncRNAs at the molecular level in mammalian cells.
</p>