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      Safety and Efficacy of Tirofiban Combined with Statins in the Perioperative Period of Intracranial Aneurysms: Systematic Review and Meta-Analysis

      research-article
      1 , 2 , 3 , 1 ,
      Computational and Mathematical Methods in Medicine
      Hindawi

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          Abstract

          Objective

          In order to verify the safety and effectiveness of tirofiban combined with statins in the perioperative period of intracranial aneurysms, this study adopts systematic review and meta-analysis, so as to comprehensively understand the situation of intracranial aneurysms in the perioperative period, and tirofiban combined with statins was finally determined as an effective treatment drug.

          Methods

          This study used systematic retrospective analysis and selected 80 patients with intracranial aneurysms treated in our hospital from June 2021 to June 2022 as the research objects. Through conventional drugs and tirofiban combined with statins used in this study, the intracranial levels, the probability of aneurysm rupture, and postoperative complications of the two groups were observed and recorded.

          Results

          The analysis of 80 patients with intracranial aneurysms showed that the influence of intracranial levels in the observation group was better than that in the reference group, the rupture of aneurysms in the observation group was lower than that in the reference group, and the incidence of postoperative complications in the observation group was lower than that in the reference group.

          Conclusion

          Through simulation verification, it is concluded that tirofiban combined with statins is safe and effective in the perioperative application of intracranial aneurysms. This drug can improve vascular recanalization, reduce the incidence of cerebrovascular disease events, and reduce the incidence of rebleeding. Its therapeutic effect is worthy of wide clinical application and promotion.

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          Most cited references13

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          Tirofiban’s single center experience in the treatment of stent thrombosis in intracranial aneurysms

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            • Abstract: not found
            • Article: not found

            Clinical significance of morphological and hemodynamic characteristics of intracranial aneurysms in predicting the risk of rupture

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              • Record: found
              • Abstract: not found
              • Article: not found

              Effect of perioperative nursing combined with hyperbaric oxygen chamber treatment in patients with intracranial aneurysms

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                Author and article information

                Contributors
                Journal
                Comput Math Methods Med
                Comput Math Methods Med
                cmmm
                Computational and Mathematical Methods in Medicine
                Hindawi
                1748-670X
                1748-6718
                2022
                30 September 2022
                : 2022
                : 8264261
                Affiliations
                1Department of Neurosurgery, The Second Hospital of Yulin, Yilin City Shaanxi Province 719000, China
                2Department of Neurology, The First Hospital of Yulin, Shaanxi Province 719000, China
                3Department of Neurosurgery, The First Hospital of Yulin, Shaanxi Province 719000, China
                Author notes

                Academic Editor: Pan Zheng

                Author information
                https://orcid.org/0000-0003-3663-4307
                Article
                10.1155/2022/8264261
                9553357
                67049dcf-a44a-406a-bde9-60ee6d18d57a
                Copyright © 2022 Ming Hao et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 12 August 2022
                : 25 August 2022
                : 5 September 2022
                Categories
                Research Article

                Applied mathematics
                Applied mathematics

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