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      Predicting Non-Mass Breast Cancer Utilizing Ultrasound and Molybdenum Target X-Ray Characteristics

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          Abstract

          Objective

          The aim of this study is to investigate the influence of ultrasound and molybdenum target X-ray characteristics in predicting non-mass breast cancer.

          Methods

          A retrospective analysis was conducted on the clinical data of 185 patients presenting with non-mass breast lesions between September 2019 and 2021. The non-mass lesions were categorized into benign and malignant types based on ultrasonographic findings, which included lamellar hypoechoic, ductal alteration, microcalcification, and structural disorder types. Furthermore, an examination was undertaken to discern variances in molybdenum target X-ray parameters, ultrasonographic manifestations, and characteristics among individuals diagnosed with non-mass breast lesions.

          Results

          The ultrasonographic depiction of microcalcified lesions and the identification of suspicious malignancy through molybdenum target X-ray evaluation exhibited independent associations with non-mass breast cancer, yielding statistically significant differences ( p < 0.05). Subsequently, the logistic regression model was formulated as follows: Logit (P) =−1.757+2.194* microcalcification type on ultrasound + 1.520* suspicious malignancy on molybdenum target X-ray evaluation. The respective areas under the receiver operating characteristic curves for microcalcification type on ultrasound, suspicious malignancy on molybdenum target X-ray, and the integrated diagnostic model were 0.733, 0.667, and 0.827, respectively, demonstrating discriminative capacities.

          Conclusion

          Using both ultrasound and molybdenum target X-ray diagnostics can increase the accuracy of non-mass breast cancer detection. The findings of this study have the potential to augment the detection rate of non-lumpy breast cancer and provide an imaging basis for enhancing the prognosis of individuals with breast cancer.

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          Most cited references35

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          Nomogram based on radiomics analysis of primary breast cancer ultrasound images: prediction of axillary lymph node tumor burden in patients

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            Potential role of shear-wave ultrasound elastography for the differential diagnosis of breast non-mass lesions: preliminary report.

            To report our preliminary experience with shear-wave elastography (SWE) for non-mass lesions (NMLs) in the breast and suggest a potential ancillary role of SWE for BI-RADS Category 4a NMLs in reducing the number of unnecessary benign biopsies.
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              Non-mass-like lesions on breast ultrasonography: a systematic review.

              This article reviews various non-mass-like ultrasonography (US) findings of the breast and the sonographic-pathologic correlation with Doppler techniques, elastography, and MRI. High-resolution US allows for identification of small, clinically occult non-mass-like US findings. Ductal carcinoma in situ and invasive lobular carcinoma usually manifest as a non-mass-like lesion on US. It is useful to classify non-mass-like lesions on US in a similar manner to the classification of non-mass-like enhancement on MRI.
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                Author and article information

                Journal
                J Multidiscip Healthc
                J Multidiscip Healthc
                jmdh
                Journal of Multidisciplinary Healthcare
                Dove
                1178-2390
                02 September 2024
                2024
                : 17
                : 4267-4276
                Affiliations
                [1 ]School of Medical Imaging, First Hospital of Shanxi Medical University , Taiyuan, Shanxi, People’s Republic of China
                [2 ]The Seventh Medical Center of the Chinese People’s Liberation, Army General Hospital , Beijing, People’s Republic of China
                Author notes
                Correspondence: Chunmei Jia, School of Medical Imaging, First Hospital of Shanxi Medical University , No. 85, South Jiefang Road, Taiyuan, 100007, Shanxi, People’s Republic of China, Tel +86 13643667836, Email jcmc6606@126.com
                Article
                473370
                10.2147/JMDH.S473370
                11378988
                39246563
                663b9c16-2c07-477e-984a-ea8a9c13adcc
                © 2024 Wang et al.

                This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms ( https://www.dovepress.com/terms.php).

                History
                : 24 June 2024
                : 20 August 2024
                Page count
                Figures: 3, Tables: 5, References: 36, Pages: 10
                Funding
                Funded by: contrast-enhanced ultrasound features and molecular biological prognostic indicators of breast cancer, Key Research and Development Program of Shanxi Province;
                Correlation between contrast-enhanced ultrasound features and molecular biological prognostic indicators of breast cancer, Key Research and Development Program of Shanxi Province (Social development, No.: 201803D31097).
                Categories
                Original Research

                Medicine
                correlation,logistic regression,molybdenum targeted x-ray,non-mass type,ultrasonographic manifestations

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