Shared principles in NF-kappaB signaling.

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Abstract

The transcription factor NF-kappaB has served as a standard for inducible transcription factors for more than 20 years. The numerous stimuli that activate NF-kappaB, and the large number of genes regulated by NF-kappaB, ensure that this transcription factor is still the subject of intense research. Here, we attempt to synthesize some of the basic principles that have emerged from studies of NF-kappaB, and we aim to generate a more unified view of NF-kappaB regulation.

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Journal

Journal ID (iso-abbrev): Cell

Title: Cell

Publisher: Elsevier BV

ISSN (Electronic): 1097-4172

ISSN (Print): 0092-8674

Publication date (Electronic): Feb 08 2008

Volume: 132

Issue: 3

Affiliations

[1 ] Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.

Article

Publisher Item ID: S0092-8674(08)00120-7

DOI: 10.1016/j.cell.2008.01.020

PubMed ID: 18267068

SO-VID: 650e7198-dd73-4d9f-9da9-66ddd39fcf62

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