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      Application of Polypodiopsida Class in Nanotechnology–Potential towards Development of More Effective Bioactive Solutions

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          Abstract

          The area of phytosynthesized nanomaterials is rapidly developing, with numerous studies being published yearly. The use of plant extracts is an alternative method to reduce the toxic potential of the nanomaterials and the interest in obtaining phytosynthesized nanoparticles is usually directed towards accessible and common plant species, ferns not being explored to their real potential in this field. The developed nanoparticles could benefit from their superior antimicrobial and antioxidant properties (compared with the nanoparticles obtained by other routes), thus proposing an important alternative against health care-associated and drug-resistant infections, as well as in other types of applications. The present review aims to summarize the explored application of ferns in nanotechnology and related areas, as well as the current bottlenecks and future perspectives, as emerging from the literature data.

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          Most cited references165

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          Silver nanoparticles as a new generation of antimicrobials.

          Silver has been in use since time immemorial in the form of metallic silver, silver nitrate, silver sulfadiazine for the treatment of burns, wounds and several bacterial infections. But due to the emergence of several antibiotics the use of these silver compounds has been declined remarkably. Nanotechnology is gaining tremendous impetus in the present century due to its capability of modulating metals into their nanosize, which drastically changes the chemical, physical and optical properties of metals. Metallic silver in the form of silver nanoparticles has made a remarkable comeback as a potential antimicrobial agent. The use of silver nanoparticles is also important, as several pathogenic bacteria have developed resistance against various antibiotics. Hence, silver nanoparticles have emerged up with diverse medical applications ranging from silver based dressings, silver coated medicinal devices, such as nanogels, nanolotions, etc.
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            Plant products as antimicrobial agents.

            The use of and search for drugs and dietary supplements derived from plants have accelerated in recent years. Ethnopharmacologists, botanists, microbiologists, and natural-products chemists are combing the Earth for phytochemicals and "leads" which could be developed for treatment of infectious diseases. While 25 to 50% of current pharmaceuticals are derived from plants, none are used as antimicrobials. Traditional healers have long used plants to prevent or cure infectious conditions; Western medicine is trying to duplicate their successes. Plants are rich in a wide variety of secondary metabolites, such as tannins, terpenoids, alkaloids, and flavonoids, which have been found in vitro to have antimicrobial properties. This review attempts to summarize the current status of botanical screening efforts, as well as in vivo studies of their effectiveness and toxicity. The structure and antimicrobial properties of phytochemicals are also addressed. Since many of these compounds are currently available as unregulated botanical preparations and their use by the public is increasing rapidly, clinicians need to consider the consequences of patients self-medicating with these preparations.
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              A community-derived classification for extant lycophytes and ferns

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                Author and article information

                Contributors
                Role: Academic Editor
                Role: Academic Editor
                Journal
                Antioxidants (Basel)
                Antioxidants (Basel)
                antioxidants
                Antioxidants
                MDPI
                2076-3921
                08 May 2021
                May 2021
                : 10
                : 5
                : 748
                Affiliations
                [1 ]National Institute for Research & Development in Chemistry and Petrochemistry-ICECHIM, 060021 Bucharest, Romania; irina.fierascu@ 123456icechim.ro
                [2 ]Faculty of Horticulture, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 011464 Bucharest, Romania
                [3 ]Department of Science and Engineering of Oxide Materials and Nanomaterials, University “Politehnica” of Bucharest, 011061 Bucharest, Romania
                [4 ]Department of General Chemistry, University “Politehnica” of Bucharest, 011061 Bucharest, Romania
                [5 ]Department of Natural Sciences, University of Pitesti, 1 Targu din Vale Str., 110040 Pitesti, Romania; oana.draghiceanu@ 123456upit.ro (O.A.D.); cristina.soare@ 123456upit.ro (L.C.S.)
                Author notes
                [* ]Correspondence: fierascu.radu@ 123456icechim.ro (R.C.F.); camelia.ungureanu@ 123456upb.ro (C.U.); Tel.: +40-723-239-120 (C.U.); Fax: +40-213-153-299 (R.C.F.); +40-214-023-930 (C.U.)
                Author information
                https://orcid.org/0000-0002-1834-9812
                https://orcid.org/0000-0003-4224-9157
                Article
                antioxidants-10-00748
                10.3390/antiox10050748
                8151343
                6473e880-6cd8-474b-b02c-023e3e7102d0
                © 2021 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( https://creativecommons.org/licenses/by/4.0/).

                History
                : 15 April 2021
                : 05 May 2021
                Categories
                Review

                phytosynthesis,antioxidant,antimicrobial,polypodiopsida,nanotechnology

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