ABSTRACT Background: Condylar hyperplasia (CH) is excessive growth of either mandibular condyle leading to facial asymmetry [1]. The aim of this study was to access the condylar growth by 99mTc-MDP SPECT-CT bone scan, and compared the results with age matched control groups. Methods: 57 patients of age 10-30 years were enrolled, 26/57 were diseased with CH and 31/57 belong to control group. Both groups were divided into group A (10-20 years) and group B (21-30years). All underwent 99mTc-MDP SPECT-CT bone scan of head region. The condyle to L4 vertebra ratio on planner and condyle to clivus ratio on summed SPECT images were measured. The mandibular deviation was measured in diseased group on the coronal view of 3D CT reconstruction image of the head. Results: Both SPECT and planner parameters classified 17/26 patients as active CH. The mean condyle to clivus ratio and condyle to L4 vertebra ratio of active condyles is higher than control group, (p =