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Age-associated decrease in serum glial cell line-derived neurotrophic factor levels in patients with major depressive disorder.
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Abstract
Many studies have supported the role of neurotrophic hypothesis in the pathophysiology of mood disorders. This study examined serum levels of glial cell line-derived neurotrophic factor (GDNF), one of the neurotrophic factors, in patients with major depressive disorder (MDD) at different disease states.