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      Investigation of the 8-hydroxy-2'-deoxyguanosine, total antioxidant and nitric oxide levels of serum in dogs infected with Babesia vogeli.

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          Abstract

          Oxidative stress was defined as corruption of balance between oxidant-antioxidant states in favor of oxidants. In this study, it was aimed to determine oxidative stress in naturally infected dogs with Babesia vogeli. The 8-hydroxy-2'-deoxyguanosine (8-OHdG), nitric oxide (NO) and total antioxidant capacity (TAC) levels in the sera were analyzed by ELISA. 8-OHdG levels increased in B. vogeli infected dogs compared to control group (P<0.05). Also, NO levels increased while TOC levels decreased in B. vogeli infected dogs but these variations were not found as statistically important (P>0.05).

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Vet. Parasitol.
          Title: Veterinary parasitology
          ISSN (Electronic): 1873-2550
          ISSN (Print): 0304-4017
          Publication date (Electronic): Aug 29 2014
          Volume: 204
          Issue: 3-4
          Affiliations
          [1 ] Department of Biochemistry, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55200 Atakum, Samsun, Turkey. Electronic address: gciftci@omu.edu.tr.
          [2 ] Department of Internal Medicine, Faculty of Veterinary Medicine, University of Adnan Menderes, 09016 Işıklı, Aydın, Turkey.
          [3 ] Department of Parasitology, Faculty of Veterinary Medicine, University of Adnan Menderes, 09016 Işıklı, Aydın, Turkey.
          [4 ] Department of Biochemistry, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55200 Atakum, Samsun, Turkey.
          [5 ] Department of Internal Medicine, Faculty of Veterinary Medicine, University of Ondokuz Mayis, 55200 Atakum, Samsun, Turkey.
          [6 ] High School of Health, University of Ondokuz Mayis, 55200 Atakum, Samsun, Turkey.
          Article
          Publisher Item ID: S0304-4017(14)00281-7
          DOI: 10.1016/j.vetpar.2014.05.002
          PubMed ID: 24882747
          SO-VID: 62a062c0-82e5-43e7-b65c-c8597dad37a5
          Copyright © Copyright © 2014 Elsevier B.V. All rights reserved.
          History

          Keywords: 8-Hydroxy-2′-deoxyguanosine,Babesia vogeli,Nitric oxide,Oxidative stress,Total antioxidant capacity
          Data availability:
          Keywords: 8-Hydroxy-2′-deoxyguanosine, Babesia vogeli, Nitric oxide, Oxidative stress, Total antioxidant capacity

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