Contributors
Jianqiu Xiao: Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Writing – review & editing
Chun Wang: Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Writing – review & editing
Juo-Chin Yao: Role: Formal analysisRole: Funding acquisitionRole: Methodology
Yael Alippe: Role: Data curationRole: Formal analysisRole: MethodologyRole: Writing – review &
editing
Tong Yang: Role: Formal analysisRole: Methodology
Dustin Kress: Role: Data curationRole: Formal analysisRole: Methodology
Kai Sun: Role: Data curationRole: Formal analysisRole: Methodology
Kourtney L. Kostecki: Role: Data curationRole: Formal analysisRole: Methodology
Joseph B. Monahan: Role: ResourcesRole: SupervisionRole: Writing – review & editing
Deborah J. Veis:
ORCID: http://orcid.org/0000-0001-7101-5582
Role: MethodologyRole: ResourcesRole: Writing – review & editing
Yousef Abu-Amer:
ORCID: http://orcid.org/0000-0002-5890-5086
Role: MethodologyRole: ResourcesRole: Writing – review & editing
Daniel C. Link: Role: MethodologyRole: ResourcesRole: Writing – review & editing
Gabriel Mbalaviele:
ORCID: http://orcid.org/0000-0003-4660-0952
Role: Formal analysisRole: Funding acquisitionRole: InvestigationRole: MethodologyRole:
Project administrationRole: ResourcesRole: SupervisionRole: Writing – original draftRole:
Writing – review & editing
Feng Shao: Role: Academic Editor
Journal
Journal ID (nlm-ta): PLoS Biol
Journal ID (iso-abbrev): PLoS Biol
Journal ID (publisher-id): plos
Journal ID (pmc): plosbiol
Title:
PLoS Biology
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1544-9173
ISSN
(Electronic):
1545-7885
Publication date
(Electronic):
6
August
2020
Publication date Collection:
August
2020
Publication date PMC-release: 6
August
2020
Volume: 18
Issue: 8
Electronic Location Identifier: e3000807
Affiliations
[1
]
Division of Bone and Mineral Diseases, Washington University School of Medicine, St.
Louis, Missouri, United Sates of America
[2
]
Division of Oncology, Washington University School of Medicine, St. Louis, Missouri,
United Sates of America
[3
]
Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi,
China
[4
]
Aclaris Therapeutics, Inc., St. Louis, Missouri, United Sates of America
[5
]
Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis,
Missouri, United Sates of America
[6
]
Shriners Hospital for Children, St. Louis, Missouri, United Sates of America
National Institute of Biological Sciences, CHINA
Author notes
I have read the journal's policy and the authors of this manuscript have the following
competing interests: GM is a consultant for Aclaris Therapeutics. KLK and JBM are
employees of Aclaris Therapeutics.
Author information
Article
Publisher ID:
PBIOLOGY-D-20-00765
DOI: 10.1371/journal.pbio.3000807
PMC ID: 7446913
PubMed ID: 32760056
SO-VID: 61e9acb2-5040-42da-9274-c8b162635449
Copyright © © 2020 Xiao et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 25
March
2020
Date
accepted
: 20
July
2020
Page count
Figures: 4,
Tables: 0,
Pages: 19
Funding
Funded by: funder-id http://dx.doi.org/10.13039/100000069, National Institute of Arthritis and Musculoskeletal and Skin Diseases;
Award ID: AR068972
Award Recipient
:
ORCID: http://orcid.org/0000-0003-4660-0952
Gabriel Mbalaviele
Funded by: funder-id http://dx.doi.org/10.13039/100000069, National Institute of Arthritis and Musculoskeletal and Skin Diseases;
Award ID: AR076758
Award Recipient
:
ORCID: http://orcid.org/0000-0003-4660-0952
Gabriel Mbalaviele
Funded by: funder-id http://dx.doi.org/10.13039/100000069, National Institute of Arthritis and Musculoskeletal and Skin Diseases;
Award ID: AR049192
Award Recipient
:
ORCID: http://orcid.org/0000-0002-5890-5086
Yousef Abu-Amer
Funded by: funder-id http://dx.doi.org/10.13039/100000069, National Institute of Arthritis and Musculoskeletal and Skin Diseases;
Award ID: AR054326
Award Recipient
:
ORCID: http://orcid.org/0000-0002-5890-5086
Yousef Abu-Amer
Funded by: funder-id http://dx.doi.org/10.13039/100000069, National Institute of Arthritis and Musculoskeletal and Skin Diseases;
Award ID: AR072623
Award Recipient
:
ORCID: http://orcid.org/0000-0002-5890-5086
Yousef Abu-Amer
Funded by: funder-id http://dx.doi.org/10.13039/100011781, Shriners Hospitals for Children;
Award ID: 85160
Award Recipient
:
ORCID: http://orcid.org/0000-0002-5890-5086
Yousef Abu-Amer
Funded by: funder-id http://dx.doi.org/10.13039/100000069, National Institute of Arthritis and Musculoskeletal and Skin Diseases;
Award ID: AR052705
Award Recipient
:
ORCID: http://orcid.org/0000-0001-7101-5582
Deborah J. Veis
Funded by: funder-id http://dx.doi.org/10.13039/100000069, National Institute of Arthritis and Musculoskeletal and Skin Diseases;
Award ID: AR073507
Award Recipient
:
ORCID: http://orcid.org/0000-0001-7101-5582
Deborah J. Veis
Funded by: funder-id http://dx.doi.org/10.13039/100011781, Shriners Hospitals for Children;
Award ID: 85117
Award Recipient
:
ORCID: http://orcid.org/0000-0001-7101-5582
Deborah J. Veis
This work was supported by NIH/NIAMS AR068972 and AR076758 grants to GM. DJV was supported
by NIH grants AR052705 and AR073507 and grant 85117 from Shriners Hospitals for Children.
YA-A was supported by NIH grants AR049192, AR054326, AR072623 and by grant #85160
from the Shriners Hospital for Children. The funders had no role in study design,
data collection and analysis, decision to publish, or preparation of the manuscript.
Categories
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