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      Non-classical presentation of vitamin D deficiency: a case report

      case-report

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          Abstract

          Background

          Vitamin D is a fat-soluble vitamin; vitamin D is essential to sustain health and it protects against osteoporosis. It is crucial to the human body’s physiology in terms of muscular movement and neurological signal transmission, and to the immune system in defense against invading pathogens.

          Case presentation

          This was a case of a 26-year-old Sudanese woman who presented with a 2-year history of anosmia, recurrent nasal polyps, back pain, and chronic fatigue. She was diagnosed as having a case of vitamin D deficiency and responded well to treatment.

          Conclusion

          There is an association between vitamin D deficiency and recurrent allergic nasal conditions.

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          Most cited references3

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          Chronic Rhinosinusitis with Nasal Polyps.

          Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed by the presence of both subjective and objective evidence of chronic sinonasal inflammation. Symptoms include anterior or posterior rhinorrhea, nasal congestion, hyposmia, and/or facial pressure or pain that last for a duration of more than 12 weeks. Nasal polyps are inflammatory lesions that project into the nasal airway, are typically bilateral, and originate from the ethmoid sinus. Males are more likely to be affected than females, but no specific genetic or environmental factors have been strongly linked to the development of this disorder to date. CRSwNP is frequently associated with asthma and allergic rhinitis, but the cellular and molecular mechanisms that contribute to the clinical symptoms are not fully understood. Defects in the sinonasal epithelial cell barrier, increased exposure to pathogenic and colonized bacteria, and dysregulation of the host immune system are all thought to play prominent roles in disease pathogenesis. Additional studies are needed to further explore the clinical and pathophysiological features of CRSwNP so that biomarkers can be identified and novel advances can be made to improve the treatment and management of this disease.
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            Targeted 25-hydroxyvitamin D concentration measurements and vitamin D3 supplementation can have important patient and public health benefits

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              Vitamin D insufficiency/deficiency management.

              In recent years, vitamin D deficiency has been recognized increasingly often in patients, and different supplement regimens have been prescribed to treat it. There has been no consensus on treatment regimens. This study was conducted to determine the management of vitamin D deficiency/insufficiency in outpatient adults in northeast Tennessee.
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                Author and article information

                Contributors
                drmuhanadkamal@hotmail.com
                nimeirimust@gmail.com
                Journal
                J Med Case Rep
                J Med Case Rep
                Journal of Medical Case Reports
                BioMed Central (London )
                1752-1947
                10 August 2020
                10 August 2020
                2020
                : 14
                : 126
                Affiliations
                [1 ]Community Medicine and Epidemiology, Faculty of Medicine, Ibn Sina University, Khartoum, Sudan
                [2 ]GRID grid.440839.2, Preventive Medicine and Epidemiology, , Alneelain University, ; Khartoum, Sudan
                Article
                2454
                10.1186/s13256-020-02454-1
                7416384
                32772912
                610f98c6-093f-447e-8500-6017ffe2de3d
                © The Author(s) 2020

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 26 March 2020
                : 8 July 2020
                Categories
                Case Report
                Custom metadata
                © The Author(s) 2020

                Medicine
                vitamin d deficiency,allergy,nasal polyps,backache,chronic fatigability
                Medicine
                vitamin d deficiency, allergy, nasal polyps, backache, chronic fatigability

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