Marisela M. Davis: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: Writing – original draft
Aaron M. Brock:
ORCID: https://orcid.org/0000-0002-3861-9074
Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Writing – review & editing
Tanner G. DeHart:
ORCID: https://orcid.org/0000-0002-8165-0376
Role: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Writing – review & editing
Brittany P. Boribong:
ORCID: https://orcid.org/0000-0003-1297-6337
Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: Visualization
Katherine Lee:
ORCID: https://orcid.org/0000-0002-0654-1583
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: MethodologyRole:
Visualization
Mecaila E. McClune:
ORCID: https://orcid.org/0000-0002-9071-540X
Role: Data curationRole: Formal analysisRole: MethodologyRole: Writing – review &
editing
Yunjie Chang: Role: Data curationRole: Formal analysisRole: MethodologyRole: Visualization
Nicholas Cramer:
ORCID: https://orcid.org/0000-0003-1237-4168
Role: Data curationRole: Formal analysisRole: MethodologyRole: Writing – review &
editing
Jun Liu: Role: ConceptualizationRole: Data curationRole: Project administrationRole: ResourcesRole:
Visualization
Caroline N. Jones:
ORCID: https://orcid.org/0000-0001-6003-9335
Role: ConceptualizationRole: Data curationRole: MethodologyRole: Project administrationRole:
ResourcesRole: Writing – review & editing
Brandon L. Jutras:
ORCID: https://orcid.org/0000-0002-7989-1031
Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: Project administrationRole: ResourcesRole: SupervisionRole: Writing
– original draft
D. Scott Samuels: Role: Editor
Journal ID (nlm-ta): PLoS Pathog
Journal ID (iso-abbrev): PLoS Pathog
Journal ID (publisher-id): plos
Journal ID (pmc): plospath
Title:
PLoS Pathogens
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7366
ISSN
(Electronic):
1553-7374
Publication date
(Electronic):
13
May
2021
Publication date Collection:
May
2021
Volume: 17
Issue: 5
Electronic Location Identifier: e1009546
Affiliations
[1
]
Department of Biochemistry, Virginia Tech, Blacksburg, Virginia, United States of
America
[2
]
Fralin Life Sciences Institute, Virginia Tech, Blacksburg, Virginia, United States
of America
[3
]
Molecular and Cellular Biology, Virginia Tech, Blacksburg, Virginia, United States
of America
[4
]
Genetics, Bioinformatics, and Computational Biology, Virginia Tech, Blacksburg, Virginia,
United States of America
[5
]
Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, United States
of America
[6
]
Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut,
United States of America
[7
]
Microbial Sciences Institute, Yale University, West Haven, Connecticut, United States
of America
[8
]
Center for Emerging, Zoonotic and Arthropod-borne Pathogens, Virginia Tech, Blacksburg,
Virginia, United States of America
[9
]
Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, Virginia,
United States of America
University of Montana, UNITED STATES
Author notes
All authors declare no competing interests.
[¤a]
Current address: Department of Microbiology and Immunology, Virginia Commonwealth
University, Richmond, Virginia, United States of America
[¤b]
Current address: Department of Bioengineering, University of Texas, Dallas, Texas,
United States of America
Author information
Article
Publisher ID:
PPATHOGENS-D-21-00267
DOI: 10.1371/journal.ppat.1009546
PMC ID: 8118282
PubMed ID: 33984073
SO-VID: 60f8fd73-3f9b-4384-b39a-52f0687e1692
Copyright © © 2021 Davis et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: Steven & Alexandra Cohen Foundation
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7989-1031
Brandon L. Jutras
Funded by: National Institutes Allergy and Infectious Disease
Award ID: R21AI159800-01
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7989-1031
Brandon L. Jutras
Funded by: Virginia Tech
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7989-1031
Brandon L. Jutras
Funded by: Fralin Life Sciences Institute
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7989-1031
Brandon L. Jutras
Funded by: funder-id http://dx.doi.org/10.13039/100000199, U.S. Department of Agriculture;
Award ID: VA-160113
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7989-1031
Brandon L. Jutras
Funded by: George Washington Carver Fellowship
Award Recipient
:
Mari M. Davis
Funded by: George Washington Carver Fellowship
Award Recipient
:
ORCID: https://orcid.org/0000-0002-3861-9074
Aaron M. Brock
Funding was provided in part by the Steven & Alexandra Cohen Foundation, the National
Institutes Allergy and Infectious Disease (R21AI159800-01), Virginia Tech, the Fralin
Life Sciences Institute, and the USDA (VA-160113), all awarded to BLJ. MMD and AB
are supported by a George Washington Carver Fellowship. The funders had no role in
study design, data collection and analysis, decision to publish, or preparation of
manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Borrelia
Subject:
Borrelia Burgdorferi
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Biology and Life Sciences
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Microbiology
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Medical Microbiology
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Microbial Pathogens
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Bacterial Pathogens
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Borrelia
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Borrelia Burgdorferi
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Medicine and Health Sciences
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Pathology and Laboratory Medicine
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Pathogens
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Microbial Pathogens
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Bacterial Pathogens
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Borrelia
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Cell Biology
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Cell Motility
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Cell Migration
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Developmental Biology
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Cell Migration
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Biology and Life Sciences
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Biochemistry
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Enzymology
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Enzymes
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Proteases
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Serine Proteases
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Biology and Life Sciences
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Biochemistry
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Proteins
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Enzymes
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Proteases
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Serine Proteases
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Enzymology
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Enzymes
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Biology and Life Sciences
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Proteins
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Enzymes
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Lysozyme
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Biology and Life Sciences
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Cell Biology
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Cellular Types
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Animal Cells
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Blood Cells
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White Blood Cells
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Biology and Life Sciences
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Cell Biology
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Cellular Types
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Animal Cells
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Immune Cells
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White Blood Cells
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Neutrophils
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Biology and Life Sciences
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Immunology
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Immune Cells
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White Blood Cells
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Neutrophils
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Medicine and Health Sciences
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Immunology
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Immune Cells
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White Blood Cells
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Neutrophils
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Biology and Life Sciences
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Microbiology
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Periplasm
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Research and Analysis Methods
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Chromatographic Techniques
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Liquid Chromatography
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Liquid Chromatography-Mass Spectrometry
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Physical Sciences
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Chemistry
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Analytical Chemistry
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Mass Spectrometry
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Liquid Chromatography-Mass Spectrometry
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Research and Analysis Methods
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Spectrum Analysis Techniques
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Mass Spectrometry
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Liquid Chromatography-Mass Spectrometry
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Biology and Life Sciences
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Microbiology
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Bacteriology
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Bacterial Genetics
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Biology and Life Sciences
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Microbial Genetics
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Bacterial Genetics