The use of early active motion protocols after repair of the thumb ulnar collateral ligament (UCL) theoretically could avoid the complications of postoperative immobilization and improve ligament healing. The goals of this study were as follows: (1) to develop an accurate model of acute UCL rupture, (2) to determine the strain pattern in the UCL during constrained active thumb motion in intact and repaired thumbs, and (3) to determine the load to failure and strain of the UCL during rupture in forced abduction.