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Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial.
M Overgaard
1 ,
P S Hansen ,
J Overgaard ,
C Rose ,
M Andersson ,
F Bach ,
M Kjaer ,
C C Gadeberg ,
H T Mouridsen ,
M B Jensen ,
K Zedeler
Oct 02 1997
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Abstract
Irradiation after mastectomy can reduce locoregional recurrences in women with breast cancer, but whether it prolongs survival remains controversial. We conducted a randomized trial of radiotherapy after mastectomy in high-risk premenopausal women, all of whom also received adjuvant systemic chemotherapy with cyclophosphamide, methotrexate, and fluorouracil (CMF).