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      Malignant peritoneal mesothelioma presenting as a mass in a Spigelian hernia. Report of a case

      case-report

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          Highlights

          • Cancers that occur within the abdomen and pelvis may present within a hernia.

          • Cancer presenting within a Spigelian hernia has not been previously reported.

          • Malignant peritoneal mesothelioma presented within a Spigelian hernia.

          • Peritoneal mesothelioma progressed rapidly within a hernia sac.

          Abstract

          Background

          Gastrointestinal cancer, gynecologic cancer and malignant peritoneal mesothelioma may disseminate widely to the surfaces of the abdomen and pelvis. In some patients this spread of the disease may find its way into a hernia sac.

          Methods

          The Spigelian hernia is caused by a protrusion of the peritoneum of the anterior abdominal wall into the abdominal wall muscle. This peritoneal defect occurs through the semilunar line of Spiegel in or closely associated with the semicircular line of Douglas.

          Results

          A patient presented with a large (11 cm greatest diameter) mass in the left lower quadrant. The mass was composed of malignant peritoneal mesothelioma and was anatomically located within the Spigelian hernia belt. At the time of cytoreductive surgery numerous other sites of malignant peritoneal mesothelioma were present within the abdomen and pelvis.

          Conclusions

          The left lower quadrant mass was a malignant peritoneal mesothelioma presenting within a Spigelian hernia defect. This phenomenon has not been previously reported.

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          Most cited references9

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          A review of peritoneal mesothelioma at the Washington Cancer Institute.

          This article reviews a single institution's experience with 68 patients (21 females, 47 males) prospectively treated over the last 2 decades with an aggressive local-regional approach, combining maximal cytoreductive surgery with heated intraoperative intraperitoneal chemotherapy and early postoperative intraperitoneal chemotherapy. This multimodality treatment has resulted in a median survival of 67 months. Female patients had a significantly better prognosis than males. The other significant predictive factors of survival were: age, diagnosis by incidental findings, tumor extent, pathology, and completeness of cytoreduction.
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            Spigelian hernia: surgical anatomy, embryology, and technique of repair.

            Spigelian hernia (1-2% of all hernias) is the protrusion of preperitoneal fat, peritoneal sac, or organ(s) through a congenital or acquired defect in the spigelian aponeurosis (i.e., the aponeurosis of the transverse abdominal muscle limited by the linea semilunaris laterally and the lateral edge of the rectus muscle medially). Mostly, these hernias lie in the "spigelian hernia belt," a transverse 6-cm-wide zone above the interspinal plane; lower hernias are rare and should be differentiated from direct inguinal or supravescical hernias. Although named after Adriaan van der Spieghel, he only described the semilunar line (linea Spigeli) in 1645. Josef Klinkosch in 1764 first defined the spigelian hernia as a defect in the semilunar line. Defects in the aponeurosis of transverse abdominal muscle (mainly under the arcuate line and more often in obese individuals) have been considered as the principal etiologic factor. Pediatric cases, especially neonates and infants, are mostly congenital. Embryologically, spigelian hernias may represent the clinical outcome of weak areas in the continuation of aponeuroses of layered abdominal muscles as they develop separately in the mesenchyme of the somatopleura, originating from the invading and fusing myotomes. Traditionally, repair consists of open anterior herniorraphy, using direct muscle approximation, mesh, and prostheses. Laparoscopy, preferably a totally extraperitoneal procedure, or intraperitoneal when other surgical repairs are planned within the same procedure, is currently employed as an adjunct to diagnosis and treatment of spigelian hernias. Care must be taken not to create iatrogenic spigelian hernias when using laparoscopy trocars or classic drains in the spigelian aponeurosis.
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              Epidemiologic, economic, and sociologic aspects of hernia surgery in the United States in the 1990s.

              I M Rutkow (1998)
              Such important, yet basic, questions as the percentage chance that an individual will over the course of his or her life be in need of or actually undergo a groin herniorrhaphy or the absolute number and type of hernias that exist in a given society on any particular day continue to be statistically undefined. A review of epidemiologic data provides come preliminary answers. Recent studies from the National Center for Health Statistics show that approximately 750,000 groin herniorrhaphies are completed annually in the United States. More than 80% of these operations involve the use of mesh prosthesis and are performed on an outpatient basis. Despite the large number of hernioplasties completed, the public's understanding of hernias and their management remains unsophisticated.
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                Author and article information

                Contributors
                Journal
                Int J Surg Case Rep
                Int J Surg Case Rep
                International Journal of Surgery Case Reports
                Elsevier
                2210-2612
                2210-2612
                07 March 2020
                2020
                07 March 2020
                : 68
                : 239-241
                Affiliations
                [0005]Program in Peritoneal Surface Malignancies, MedStar Washington Hospital Center, 106 Irving St., NW, Suite 3900, Washington, DC, USA
                Article
                S2210-2612(20)30146-2
                10.1016/j.ijscr.2020.03.005
                7082590
                32197222
                605331b1-2f1d-4d83-8976-0ee0d52fb9d3
                © 2020 The Author

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                : 31 January 2020
                : 2 March 2020
                Categories
                Article

                tumor cell entrapment,peritoneal metastases,hipec,intraperitoneal chemotherapy,cytoreductive surgery,peritonectomy

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