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      Irisin improves fatty acid oxidation and glucose utilization in type 2 diabetes by regulating the AMPK signaling pathway.

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          Abstract

          It has been reported that irisin regulated exercise-mediated adipocyte browning; however, the systematical effects of irisin on the metabolism of glucose and lipid in diabetes are largely unknown. In the present study, we investigated the role and underlying mechanism of irisin in glucose utilization and lipid metabolism in diabetic mice.

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          Author and article information

          Journal
          Int J Obes (Lond)
          International journal of obesity (2005)
          Springer Nature
          1476-5497
          0307-0565
          Mar 2016
          : 40
          : 3
          Affiliations
          [1 ] Department of Cardiology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
          [2 ] Department of Cardiology, The Second Artillery General Hospital of Chinese Peoples's Liberation Army, Beijing, China.
          [3 ] Department of Anesthesiology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
          [4 ] Department of Pathology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
          Article
          ijo2015199
          10.1038/ijo.2015.199
          26403433
          5fd028ba-8335-473c-a27e-902233e07ae9
          History

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