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      Current Updates on Choanal Atresia

      review-article
      1 , *
      Frontiers in Pediatrics
      Frontiers Media S.A.
      choanal atresia, human, diagnosis, children, management

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          Abstract

          Choanal atresia (CA) is a relatively uncommon but well-recognized condition characterized by the anatomical closure of the posterior choanae in the nasal cavity. Since the original description back in the early eighteenth century, there have been controversies regarding its exact pathogenesis, the optimal surgical approach, and the use of adjunct treatments such as post-surgical stenting and anti-neoplastic agents, despite of abundant literature available. The emergence and development of new technologies play a significant role in the management of this condition. This review provides a comprehensive clinical update on CA and identifies areas for future study based on the existing available literature.

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          Most cited references50

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          An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation.

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            Choanal atresia and choanal stenosis.

            Congenital narrowing of the nasal airway at the posterior choanae, which can be uni- or bilateral, is an uncommon condition in pediatric patients. The surgical management of choanal atresia varies widely in different centers. This article discusses the different surgical strategies including: dilation and stenting; trans-palatal repair; and transnasal resection utilizing endoscopic sinus surgery (ESS) techniques. The merits of stents, lasers, CT-guided surgery, and the use of additional agents including mitomycin C are reviewed, as well as the particular problems associated with managing bilateral choanal atresia in neonates.
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              Choanal atresia: embryologic analysis and evolution of treatment, a 30-year experience.

              Choanal atresia (CA) is a congenital obstruction of the posterior nasal apertures. Multiple surgical techniques have been proposed to repair the atresia. The purpose of this study is to review the basic science and embryology of CA with emphasis on the senior author's extensive experience, and refinement of the treatment of CA. In addition, we will review the outcomes after surgical correction of pediatric patients with CA. : Retrospective review of 73 pediatric patients. Demographic information was recorded, including type of CA, concomitant medical problems, surgical method, and date of last follow-up by the surgeon. Our series show a 1.6:1 ratio of unilateral atresia to bilateral atresia. The incidence in males and females is statistically equal. High-arched palate and cross-bite deformities are particularly present if the patients undergo the transpalatal approach in the first year of life. The senior author has evolved to favoring the endoscopic approach, having a minimal long-term complication rate, and low stenosis rate (12%). The first repair of choanal atresia is the one most likely to succeed. The nasal endoscopic technique is the favored technique. It has the advantages of a low restenosis rate, does not violate the palate, and does not cause the cross-bite and palate arch deformities seen in the transpalatal technique.
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                Author and article information

                Contributors
                URI : http://frontiersin.org/people/u/80097
                Journal
                Front Pediatr
                Front Pediatr
                Front. Pediatr.
                Frontiers in Pediatrics
                Frontiers Media S.A.
                2296-2360
                09 June 2015
                2015
                : 3
                : 52
                Affiliations
                [1] 1Division of Otolaryngology Head and Neck Surgery, Department of Surgery, Rutgers Robert Wood Johnson Medical School , New Brunswick, NJ, USA
                Author notes

                Edited by: Jason May, Penn State University Hershey Medical Center, USA

                Reviewed by: Henrique De Amorim Almeida, Polytechnic Institute of Leiria, Portugal; Carol Jeanne MacArthur, Oregon Health & Science University, USA

                *Correspondence: Kelvin M. Kwong, Division of Otolaryngology Head and Neck Surgery, Department of Surgery, Rutgers Robert Wood Johnson Medical School, 1 Robert Wood Johnson Place, MEB 500A, New Brunswick, NJ 08901, USA, kmtkwong@ 123456gmail.com

                Specialty section: This article was submitted to Pediatric Otolaryngology, a section of the journal Frontiers in Pediatrics

                Article
                10.3389/fped.2015.00052
                4460812
                26106591
                5fc81dd3-071a-4835-9a8f-e68cfd3d56ba
                Copyright © 2015 Kwong.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 17 February 2015
                : 24 May 2015
                Page count
                Figures: 4, Tables: 0, Equations: 0, References: 53, Pages: 7, Words: 5474
                Categories
                Pediatrics
                Review

                choanal atresia,human,diagnosis,children,management
                choanal atresia, human, diagnosis, children, management

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