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      Examining the Feasibility of Smart Blood Pressure Home Monitoring: Advancing Remote Prenatal Care in Rural Appalachia

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          Abstract

          Background:

          Hypertensive disorders of pregnancy are a leading cause of U.S. maternal morbidity and mortality. Home blood pressure (BP) monitoring can provide early detection of hypertension (HTN) outside of routine prenatal visits. Yet little is understood about how well self-monitored BP performs during pregnancy, particularly in rural America.

          Objective:

          To examine the feasibility and patient adherence to a self-monitoring BP program and to remotely collect data on pregnant women during the third trimester at a rural health clinic.

          Materials and Methods:

          A repeated-measures prospective design was used to remotely monitor home BP readings. We examined retention and persistence of weekly BP monitoring in late-stage pregnancy, differences between weekly self-monitored and clinic BP measures, the performance of self-monitored BP in early detection of pregnancy-induced HTN, and receptivity to technology-enabled prenatal monitoring.

          Results:

          A total of 30 women enrolled. Women reported high satisfaction with prenatal care, but missed 5 out of 13 clinic visits (54%). Women contributed an average of 31.2 days of home BP monitoring. Findings showed that home systolic and diastolic BP readings slightly varied from clinic readings. Women reported high health-related internet use and e-health literacy. Participants (93%, n = 25) reported a willingness to change their behavior during pregnancy in response to personalized recommendations from a smartphone. Although preliminary, we confirmed that remote monitoring can detect elevated BP earlier than in routine clinic visits.

          Conclusion:

          Findings from this study can be used to inform a novel remote monitoring protocol to improve pregnancy care in a rural care setting.

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          Most cited references38

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          STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT

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            Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact.

            This study proposes methods for blending design components of clinical effectiveness and implementation research. Such blending can provide benefits over pursuing these lines of research independently; for example, more rapid translational gains, more effective implementation strategies, and more useful information for decision makers. This study proposes a "hybrid effectiveness-implementation" typology, describes a rationale for their use, outlines the design decisions that must be faced, and provides several real-world examples. An effectiveness-implementation hybrid design is one that takes a dual focus a priori in assessing clinical effectiveness and implementation. We propose 3 hybrid types: (1) testing effects of a clinical intervention on relevant outcomes while observing and gathering information on implementation; (2) dual testing of clinical and implementation interventions/strategies; and (3) testing of an implementation strategy while observing and gathering information on the clinical intervention's impact on relevant outcomes. The hybrid typology proposed herein must be considered a construct still in evolution. Although traditional clinical effectiveness and implementation trials are likely to remain the most common approach to moving a clinical intervention through from efficacy research to public health impact, judicious use of the proposed hybrid designs could speed the translation of research findings into routine practice.
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              Coronavirus disease 2019 (COVID-19) pandemic and pregnancy

              The current coronavirus disease 2019 (COVID-19) pneumonia pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading globally at an accelerated rate, with a basic reproduction number (R0) of 2–2.5, indicating that 2–3 persons will be infected from an index patient. A serious public health emergency, it is particularly deadly in vulnerable populations and communities in which healthcare providers are insufficiently prepared to manage the infection. As of March 16, 2020, there are more than 180,000 confirmed cases of COVID-19 worldwide, with more than 7000 related deaths. The SARS-CoV-2 virus has been isolated from asymptomatic individuals, and affected patients continue to be infectious 2 weeks after cessation of symptoms. The substantial morbidity and socioeconomic impact have necessitated drastic measures across all continents, including nationwide lockdowns and border closures. Pregnant women and their fetuses represent a high-risk population during infectious disease outbreaks. To date, the outcomes of 55 pregnant women infected with COVID-19 and 46 neonates have been reported in the literature, with no definite evidence of vertical transmission. Physiological and mechanical changes in pregnancy increase susceptibility to infections in general, particularly when the cardiorespiratory system is affected, and encourage rapid progression to respiratory failure in the gravida. Furthermore, the pregnancy bias toward T-helper 2 (Th2) system dominance, which protects the fetus, leaves the mother vulnerable to viral infections, which are more effectively contained by the Th1 system. These unique challenges mandate an integrated approach to pregnancies affected by SARS-CoV-2. Here we present a review of COVID-19 in pregnancy, bringing together the various factors integral to the understanding of pathophysiology and susceptibility, diagnostic challenges with real-time reverse transcription polymerase chain reaction (RT-PCR) assays, therapeutic controversies, intrauterine transmission, and maternal−fetal complications. We discuss the latest options in antiviral therapy and vaccine development, including the novel use of chloroquine in the management of COVID-19. Fetal surveillance, in view of the predisposition to growth restriction and special considerations during labor and delivery, is addressed. In addition, we focus on keeping frontline obstetric care providers safe while continuing to provide essential services. Our clinical service model is built around the principles of workplace segregation, responsible social distancing, containment of cross-infection to healthcare providers, judicious use of personal protective equipment, and telemedicine. Our aim is to share a framework that can be adopted by tertiary maternity units managing pregnant women in the flux of a pandemic while maintaining the safety of the patient and healthcare provider at its core.
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                Author and article information

                Journal
                Telemed Rep
                Telemed Rep
                tmr
                Telemedicine Reports
                Mary Ann Liebert, Inc., publishers (140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA )
                2692-4366
                24 March 2021
                2021
                24 March 2021
                : 2
                : 1
                : 125-134
                Affiliations
                [ 1 ]North Carolina Institute for Climate Studies, North Carolina State University, Asheville, North Carolina, USA.
                [ 2 ]Department of Geography and Planning, Appalachian State University, Boone, North Carolina, USA.
                [ 3 ]Department of Obstetrics and Gynecology, Mountain Area Health Education Center, Asheville, North Carolina, USA.
                Author notes
                [*] [ * ]Address correspondence to: Jennifer D. Runkle, North Carolina Institute for Climate Studies, North Carolina State University, 151 Patton Avenue, Asheville, NC 28801-5001, USA jrrunkle@ 123456ncsu.edu
                Article
                10.1089/tmr.2020.0021
                10.1089/tmr.2020.0021
                9049804
                35720741
                5f9293d5-585e-4574-9bf7-b85994d3b4ac
                © Jennifer D. Runkle et al., 2021; Published by Mary Ann Liebert, Inc.

                This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] ( http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : Accepted December 22, 2020
                Page count
                Figures: 5, Tables: 3, References: 44, Pages: 10
                Categories
                Original Research

                pregnancy,blood pressure,remote monitoring,mobile health,rural

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