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Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial.
H C Gerstein ,
S Yusuf ,
J Bosch ,
J Pogue ,
P Sheridan ,
N Dinccag ,
M Hanefeld ,
B Hoogwerf ,
M Laakso ,
V Mohan ,
J Shaw ,
B Zinman ,
R R Holman
Sep 23 2006
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Abstract
Rosiglitazone is a thiazolidinedione that reduces insulin resistance and might preserve insulin secretion. The aim of this study was to assess prospectively the drug's ability to prevent type 2 diabetes in individuals at high risk of developing the condition.