Mid wall fibrosis on CMR with late gadolinium enhancement may predict prognosis for LVAD and transplantation risk in patients with newly diagnosed dilated cardiomyopathy-preliminary observations from a high-volume transplant centre.

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Abstract

Patients with newly diagnosed dilated cardiomyopathy (DCM) and advanced heart failure have a very high morbidity and mortality with an unpredictable clinical course. We investigated the role of cardiovascular magnetic resonance (CMR) imaging using late gadolinium enhancement (LGE) in this cohort of high-risk patients. We hypothesized that LGE has high prognostic value in primary DCM patients referred for possible transplantation/left ventricular assist device (LVAD) consideration.

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Journal

Journal ID (iso-abbrev): ESC Heart Fail

Title: ESC heart failure

Publisher: Wiley

ISSN: 2055-5822

ISSN (Print): 2055-5822

Publication date (Electronic): Dec 2015

Volume: 2

Issue: 4

Affiliations

[1 ] Division of Cardiology Allegheny General Hospital East North Ave Pittsburgh PA USA.

[2 ] Gerald McGinnis Cardiovascular Institute East North Ave Pittsburgh PA USA.

[3 ] Division of CardiologyAllegheny General HospitalEast North AvePittsburghPAUSA; Gerald McGinnis Cardiovascular InstituteEast North AvePittsburghPAUSA.

[4 ] Bon Secours Richmond Health System Sherwood Drive Colonial Heights VA 23834 USA.

[5 ] Division of Pathology Allegheny General Hospital East North Ave Pittsburgh PA USA.

Article

Publisher Item ID: EHF212041

DOI: 10.1002/ehf2.12041

PMC ID: 5034795

PubMed ID: 27708858

SO-VID: 5cee765b-b521-4609-9646-7c647158be23

History

Keywords: Midwall fibrosis,Cardiac MRI,Heart transplantation

Data availability:

Keywords: Midwall fibrosis, Cardiac MRI, Heart transplantation

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