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      Long-Term Fenofibrate Treatment in Primary Biliary Cholangitis Improves Biochemistry but Not the UK-PBC Risk Score.

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          Abstract

          Fenofibrate (FF) has been suggested as a second-line agent in primary biliary cholangitis (PBC) patients who do not achieve adequate biochemical response to ursodeoxycholic acid (UDCA) monotherapy. Limited data exist on FF use beyond 12 months, and its long-term effects are unclear.

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          Author and article information

          Journal
          Dig. Dis. Sci.
          Digestive diseases and sciences
          Springer Nature
          1573-2568
          0163-2116
          October 2016
          : 61
          : 10
          Affiliations
          [1 ] NIHR Newcastle Biomedical Research Centre, Framlington Place, Newcastle University, Newcastle upon Tyne, UK. Vinod.hegade@ncl.ac.uk.
          [2 ] Department of Hepatology, Freeman Hospital, The Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK. Vinod.hegade@ncl.ac.uk.
          [3 ] Institute of Cellular Medicine, Faculty of Medical Sciences, William Leech Building, Framlington Place, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. Vinod.hegade@ncl.ac.uk.
          [4 ] Department of Hepatology, Freeman Hospital, The Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.
          [5 ] Institute of Cellular Medicine, Faculty of Medical Sciences, William Leech Building, Framlington Place, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
          [6 ] NIHR Newcastle Biomedical Research Centre, Framlington Place, Newcastle University, Newcastle upon Tyne, UK.
          Article
          10.1007/s10620-016-4250-y
          10.1007/s10620-016-4250-y
          27435324
          5cb24614-d581-4ecc-b3cc-b048e324feb2
          History

          Prognosis,PBC,Fenofibrate,UK-PBC Risk Score,UDCA
          Prognosis, PBC, Fenofibrate, UK-PBC Risk Score, UDCA

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