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      Can Clinical Measures of Postoperative Binocular Function Predict the Long-Term Stability of Postoperative Alignment in Intermittent Exotropia?

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          Abstract

          Purpose

          To evaluate whether clinical measures of postoperative binocular functions could predict the long-term stability of postoperative ocular alignment in children with intermittent exotropia.

          Methods

          A retrospective study was performed in thirty-nine children (median: 7 years) who have been surgically treated from intermittent exotropia without overcorrection (less than 10 prism diopters [pd] of exodeviation at 1 month postoperatively). Angles of deviation and binocular functions were measured preoperatively and at 1 month, 6 months, and the final follow-up visit (≥24 months) postoperatively. We examined the relationships between postoperative drift (change of ocular alignment) and binocular functions (sensory fusion, fusional convergence amplitude, and stereoacuity).

          Results

          The surgical success rate (esophoria/tropia ≤5 pd to exophoria/tropia ≤10 pd) dropped to 76.9% at 6 months after surgery and to 53.8% at individuals' last visit (mean: 37 months). The mean exodrift was 7.7 ± 9.2 pd from the postoperative month 1 to the final visit ( p < 0.001) on distance fixation. Distance stereoacuity, central fusion, and fusional convergence amplitude significantly improved following surgery ( p < 0.05). However, no significant correlation was found between their binocular functions measured at the beginning of each follow-up period and the postoperative drift (all p > 0.13).

          Conclusion

          Our findings suggest that the clinical measures of sensory fusion, fusional convergence amplitude, and stereoacuity cannot serve as a robust predictor for the long-term stability of postoperative ocular alignment in patients who underwent successful surgery without overcorrection at 1 month postoperatively.

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          Most cited references43

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          Incidence and types of childhood exotropia: a population-based study.

          To determine the incidence and types of childhood exotropia in a defined population. Retrospective, population-based cohort. All pediatric ( or=10 prism diopters) from January 1, 1985 through December 31, 1994. The medical records of all potential patients identified by the resources of the Rochester Epidemiology Project were reviewed. Incidence and types of childhood exotropia. Two hundred five cases of childhood exotropia were identified during the 10-year period, yielding an annual age- and gender-adjusted incidence of 64.1 (95% confidence interval: 55.2-72.9)/100,000 patients younger than 19 years. This rate corresponds to a prevalence of approximately 1.0% of all children younger than 11 years, with a significant decrease in the incidence during the second decade of life (P<0.001). Eighty-six percent of the children had intermittent exotropia, convergence insufficiency, or an exotropia in the setting of an abnormal central nervous system. The incidence of childhood exotropia from this population-based study is comparable to the prevalence rates in prior reports. Exotropia is most prevalent during the first decade of life, with intermittent exotropia and convergence insufficiency occurring most frequently.
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            Stereo vision and strabismus.

            J. Read (2015)
            Binocular stereopsis, or stereo vision, is the ability to derive information about how far away objects are, based solely on the relative positions of the object in the two eyes. It depends on both sensory and motor abilities. In this review, I briefly outline some of the neuronal mechanisms supporting stereo vision, and discuss how these are disrupted in strabismus. I explain, in some detail, current methods of assessing stereo vision and their pros and cons. Finally, I review the evidence supporting the clinical importance of such measurements.
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              Long-term results of the surgical management of intermittent exotropia.

              To examine long-term surgical success rates (>10 years) for patients with intermittent exotropia and the risk factors for failure of surgery in these patients.
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                Author and article information

                Contributors
                Journal
                J Ophthalmol
                J Ophthalmol
                JOPH
                Journal of Ophthalmology
                Hindawi
                2090-004X
                2090-0058
                2020
                21 July 2020
                : 2020
                : 7392165
                Affiliations
                1The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China
                2McGill Vision Research, Department of Ophthalmology and Visual Sciences, McGill University, Montreal, QC, Canada
                Author notes

                Academic Editor: Biju B. Thomas

                Author information
                https://orcid.org/0000-0003-4220-344X
                https://orcid.org/0000-0001-5599-4151
                Article
                10.1155/2020/7392165
                7391110
                32774909
                5c6defb6-5cc1-4ecc-b8c5-e057a9ec3d43
                Copyright © 2020 Yidong Wu et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 27 January 2020
                : 24 May 2020
                : 13 June 2020
                Funding
                Funded by: Natural Science Foundation of Zhejiang Province
                Award ID: LY19H120004
                Funded by: Zhejiang Provincial Medical Health Project
                Award ID: 2019KY110
                Categories
                Research Article

                Ophthalmology & Optometry
                Ophthalmology & Optometry

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