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Abstract
Monocular training on a one-trial passive avoidance task in the young chick has been
shown to establish an engram in the forebrain hemisphere contralateral to the trained
eye, and hence interocular transfer of this task must involve the naive hemisphere
making access to the engram in the opposite hemisphere. We have studied the consequences
for the untrained hemisphere of accessing a unilateral engram during two short term
stages of its consolidation, by conducting interocular transfer tests at 7.5 min and
30 min after learning, prior to onset of amnesia induced by intracranial injection
of ouabain or cycloheximide. Testing the naive hemisphere 24 h later indicated that
engram transfer had occurred in chicks receiving one access trial at 7.5 min, during
the first stage of consolidation of the unilateral engram. At 30 min, during second
consolidation stage, five access trials were required to achieve engram transfer.
These experiments confirm the findings from the rat that engram transfer can follow
from making access to the unilateral engram. However, it has not previously been recognised
that interhemispheric memory transfer depends on the recency of formation of the unilateral
engram.