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      Effect of Tai Ji and/or Qigong on patients with stable chronic obstructive pulmonary disease: A meta-analysis and systematic review

      research-article
      , MS a , , MD b , * ,
      Medicine
      Lippincott Williams & Wilkins
      COPD, meta-analysis, Qigong, systematic review, Tai Ji

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          Abstract

          Background:

          Chronic obstructive pulmonary disease (COPD) is a global health problem with high morbidity and mortality. Tai Ji and Qigong are traditional Chinese meditative movements, benefit COPD patient’s physical and mental health.

          Methods:

          We searched the following 7 databases Web of Science, EBSCO, Medline, PubMed, CINAHL, Cochrane Library online, and CNKI from inception to July 2023. Any RCTs managed with Tai Ji and/or Qigong on stable COPD were eligible without age, and comparison management restrict, however should be published in English. Outcome measures comprised pulmonary function, 6WMT, physical and/or cognitive function, and any assessment of people QoL.

          Results:

          Tai Ji and/or Qigong significant increased %PredFEV1 on stable COPD people (MD: 3.46, 95% CI: 1.69–5.23), and 6MWT (MD: 45.07, 95% CI: 31.16–58.97). 5/6 studies reported a meaningful change in CAT/SGRQ total (MD: −4.04, 95% CI: −7.76 to −0.32; MD: −11.95, 95% CI: −21.22 to −2.68). However, 6MWT, CAT and SGRO total were debated on high heterogeneity.

          Conclusion:

          Tai Ji and Qigong increase %PredFEV1 and promote QoL. However, the evidences are not sufficient, a proper subgroup analysis should be considered.

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          Most cited references30

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          Updated guidance for trusted systematic reviews: a new edition of the Cochrane Handbook for Systematic Reviews of Interventions

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            Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study

            Although exposure to cigarette smoking and air pollution is common, the current prevalence of chronic obstructive pulmonary disease (COPD) is unknown in the Chinese adult population. We conducted the China Pulmonary Health (CPH) study to assess the prevalence and risk factors of COPD in China.
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              The global economic burden of chronic obstructive pulmonary disease for 204 countries and territories in 2020–50: a health-augmented macroeconomic modelling study

              Summary Background Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide and imposes a substantial economic burden. Gaining a thorough understanding of the economic implications of COPD is an important prerequisite for sound, evidence-based policy making. We aimed to estimate the macroeconomic burden of COPD for each country and establish its distribution across world regions. Methods In this health-augmented macroeconomic modelling study we estimated the macroeconomic burden of COPD for 204 countries and territories over the period 2020–50. The model accounted for (1) the effect of COPD mortality and morbidity on labour supply, (2) age and sex specific differences in education and work experience among those affected by COPD, and (3) the impact of COPD treatment costs on physical capital accumulation. We obtained data from various public sources including the Global Burden of Disease Study 2019, the World Bank database, and the literature. The macroeconomic burden of COPD was assessed by comparing gross domestic product (GDP) between a scenario projecting disease prevalence based on current estimates and a counterfactual scenario with zero COPD prevalence from 2020 to 2050. Findings Our findings suggest that COPD will cost the world economy INT$4·326 trillion (uncertainty interval 3·327–5·516; at constant 2017 prices) in 2020–50. This economic effect is equivalent to a yearly tax of 0·111% (0·085–0·141) on global GDP. China and the USA face the largest economic burdens from COPD, accounting for INT$1·363 trillion (uncertainty interval 1·034–1·801) and INT$1·037 trillion (0·868–1·175), respectively. Interpretation The macroeconomic burden of COPD is large and unequally distributed across countries, world regions, and income levels. Our study stresses the urgent need to invest in global efforts to curb the health and economic burdens of COPD. Investments in effective interventions against COPD do not represent a burden but could instead provide substantial economic returns in the foreseeable future. Funding Alexander von Humboldt Foundation, National Natural Science Foundation of China, CAMS Innovation Fund for Medical Science, Chinese Academy of Engineering project, Chinese Academy of Medical Sciences and Peking Union Medical College project, and Horizon Europe. Translations For the Chinese and German translations of the abstract see Supplementary Materials section.
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                Author and article information

                Contributors
                Journal
                Medicine (Baltimore)
                Medicine (Baltimore)
                MD
                Medicine
                Lippincott Williams & Wilkins (Hagerstown, MD )
                0025-7974
                1536-5964
                31 January 2025
                31 January 2025
                : 104
                : 5
                : e41390
                Affiliations
                [a ] Nanjing University of Chinese Medicine, Nanjing, China
                [b ]Department of Respiratory, Xinglong Community Health Center, Nanjing 210019, China.
                Author notes
                [* ]Correspondence: Ningchang Cheng, Department of Respiratory, Xinglong Community Health Center, Nanjing 210019, China (e-mail: chengningchang@ 123456qq.com ).
                Author information
                https://orcid.org/0000-0002-4246-4378
                Article
                MD-D-24-03941 00035
                10.1097/MD.0000000000041390
                11789891
                39889182
                5ade9555-70a3-4752-bb67-ea98b2eee655
                Copyright © 2025 the Author(s). Published by Wolters Kluwer Health, Inc.

                This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 19 April 2024
                : 10 September 2024
                : 27 September 2024
                Funding
                Funded by: Jiangsu Province Education Science 14th Five-Year Plan Key Issues
                Award ID: B/2022/01/158
                Award Recipient : Hongliang Liu
                Funded by: Nanjing Health Plaza Health Industry Open Issues
                Award ID: NJJKGC202205
                Award Recipient : Hongliang Liu
                Categories
                6700
                Research Article
                Systematic Review and Meta-Analysis
                Custom metadata
                TRUE
                T

                copd,meta-analysis,qigong,systematic review,tai ji
                copd, meta-analysis, qigong, systematic review, tai ji

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