Hannah Rees: Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
SupervisionRole: VisualizationRole: Writing – original draftRole: Writing – review
& editing
Rachel Rusholme-Pilcher: Role: Data curationRole: Formal analysisRole: Investigation
Paul Bailey: Role: Investigation
Joshua Colmer: Role: MethodologyRole: Validation
Benjamen White: Role: Validation
Connor Reynolds: Role: Data curation
Sabrina Jaye Ward: Role: Methodology
Benedict Coombes: Role: Validation
Calum A. Graham: Role: Investigation
Luíza Lane de Barros Dantas: Role: InvestigationRole: Writing – review & editing
Antony N. Dodd: Role: InvestigationRole: Writing – review & editing
Anthony Hall:
ORCID: https://orcid.org/0000-0002-1806-020X
Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
SupervisionRole: Writing – review & editing
Pamela C. Ronald: Role: Academic Editor
Journal ID (nlm-ta): PLoS Biol
Journal ID (iso-abbrev): PLoS Biol
Journal ID (publisher-id): plos
Title:
PLoS Biology
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1544-9173
ISSN
(Electronic):
1545-7885
Publication date
(Electronic):
13
October
2022
Publication date Collection:
October
2022
Publication date PMC-release: 13
October
2022
Volume: 20
Issue: 10
Electronic Location Identifier: e3001802
Affiliations
[1
]
Earlham Institute, Norwich Research Park, Norwich, United Kingdom
[2
]
Royal Botanic Gardens Kew, Richmond, Surrey, United Kingdom
[3
]
John Innes Centre, Norwich Research Park, Norwich, United Kingdom
[4
]
School of Biological Sciences, University of Bristol, Bristol, United Kingdom
University of California, Davis, UNITED STATES
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PBIOLOGY-D-22-01119
DOI: 10.1371/journal.pbio.3001802
PMC ID: 9560141
PubMed ID: 36227835
SO-VID: 5aa8ecf4-8f80-49e8-a892-ba03b52805a7
Copyright © © 2022 Rees et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/CSP1720/1
Award Recipient
:
Hannah Rees
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/CSP1720/1
Award Recipient
:
Rachel Rusholme-Pilcher
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/CSP1720/1
Award Recipient
:
ORCID: https://orcid.org/0000-0002-1806-020X
Anthony Hall
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/T/000PR9819
Award Recipient
:
Hannah Rees
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/T/000PR9819
Award Recipient
:
Rachel Rusholme-Pilcher
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/T/000PR9819
Award Recipient
:
ORCID: https://orcid.org/0000-0002-1806-020X
Anthony Hall
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/P016855/1
Award Recipient
:
Benjamen White
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/P016855/1
Award Recipient
:
Rachel Rusholme-Pilcher
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/P016855/1
Award Recipient
:
ORCID: https://orcid.org/0000-0002-1806-020X
Anthony Hall
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/T/000PR9783
Award Recipient
:
Benjamen White
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/T/000PR9783
Award Recipient
:
Rachel Rusholme-Pilcher
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/T/000PR9783
Award Recipient
:
ORCID: https://orcid.org/0000-0002-1806-020X
Anthony Hall
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/M011216/1
Award Recipient
:
Benedict Coombes
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/M011216/1
Award Recipient
:
Joshua Colmer
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/V509267/1
Award Recipient
:
Connor Reynolds
Funded by:
funder-id http://dx.doi.org/10.13039/501100000266, Engineering and Physical Sciences Research Council;
Award ID: EP/T001569/1
Award Recipient
:
Connor Reynolds
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BBS/E/T/000PR9816
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/CCG1720/1
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/N023145/1
Award Recipient
:
Paul Bailey
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/P013511/1
Award Recipient
:
Antony N. Dodd
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/P013511/1
Award Recipient
:
Luíza Lane de Barros Dantas
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/M009122/1
Award Recipient
:
Calum A. Graham
Funded by:
funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/P013511/1
Award Recipient
:
Calum A. Graham
H.R., R.R.P. and A.H. were funded by the BBSRC Core Strategic Programme Grant (Genomes
to Food Security) BB/CSP1720/1 and its constituent work package, BBS/E/T/000PR9819
(WP2 Regulatory interactions and Complex Phenotypes). B.W., R.R.P. and A.H. was supported
by the BBSRC Designing Future Wheat grant BB/P016855/1; BBS/E/T/000PR9783 (DFW WP4
Data Access and Analysis). B.C and J.C were supported by the BBSRC funded Norwich
Research Park Biosciences Doctoral Training Partnership grant BB/M011216/1. C.R. by
a BBSRC grant BB/V509267/1 and Wave 1 of The UKRI Strategic Priorities Fund under
the EPSRC Grant EP/T001569/1, particularly the “AI for Science” theme within that
grant & The Alan Turing Institute. We would also like to acknowledge BBS/E/T/000PR9816
(NC1 ‐ Supporting EI’s ISPs and the UK Community with Genomics and Single Cell Analysis)
for data generation and BB/CCG1720/1 for the physical HPC infrastructure and data
centre delivered via the NBI Computing infrastructure for Science (CiS) group. P.B.
was supported by a BBSRC TRDF grant BB/N023145/1. A.N.D., L.L.B.D. and C.A.G. are
funded by BBSRC ISP Genes in the Environment (BB/P013511/1). C.A.G. was also funded
by UK BBSRC SWBIO DTP (BB/M009122/1). The funders had no role in study design, data
collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Methods and Resources
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Plants
Subject:
Grasses
Subject:
Wheat
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Model Organisms
Subject:
Arabidopsis Thaliana
Subject:
Research and Analysis Methods
Subject:
Model Organisms
Subject:
Arabidopsis Thaliana
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Plants
Subject:
Brassica
Subject:
Arabidopsis Thaliana
Subject:
Research and Analysis Methods
Subject:
Animal Studies
Subject:
Experimental Organism Systems
Subject:
Plant and Algal Models
Subject:
Arabidopsis Thaliana
Subject:
Biology and Life Sciences
Subject:
Chronobiology
Subject:
Circadian Rhythms
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Circadian Oscillators
Subject:
Biology and Life Sciences
Subject:
Chronobiology
Subject:
Circadian Oscillators
Subject:
Biology and Life Sciences
Subject:
Chronobiology
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Organic Compounds
Subject:
Carbohydrates
Subject:
Starches
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Organic Chemistry
Subject:
Organic Compounds
Subject:
Carbohydrates
Subject:
Starches
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Plant Genomics
Subject:
Biology and Life Sciences
Subject:
Bioengineering
Subject:
Biotechnology
Subject:
Plant Biotechnology
Subject:
Plant Genomics
Subject:
Engineering and Technology
Subject:
Bioengineering
Subject:
Biotechnology
Subject:
Plant Biotechnology
Subject:
Plant Genomics
Subject:
Biology and Life Sciences
Subject:
Plant Science
Subject:
Plant Biotechnology
Subject:
Plant Genomics
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Plant Genetics
Subject:
Plant Genomics
Subject:
Biology and Life Sciences
Subject:
Plant Science
Subject:
Plant Genetics
Subject:
Plant Genomics