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      Automatic Localization of the Needle Target for Ultrasound-Guided Epidural Injections

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          Delving Deep into Rectifiers: Surpassing Human-Level Performance on ImageNet Classification

          Rectified activation units (rectifiers) are essential for state-of-the-art neural networks. In this work, we study rectifier neural networks for image classification from two aspects. First, we propose a Parametric Rectified Linear Unit (PReLU) that generalizes the traditional rectified unit. PReLU improves model fitting with nearly zero extra computational cost and little overfitting risk. Second, we derive a robust initialization method that particularly considers the rectifier nonlinearities. This method enables us to train extremely deep rectified models directly from scratch and to investigate deeper or wider network architectures. Based on our PReLU networks (PReLU-nets), we achieve 4.94% top-5 test error on the ImageNet 2012 classification dataset. This is a 26% relative improvement over the ILSVRC 2014 winner (GoogLeNet, 6.66%). To our knowledge, our result is the first to surpass human-level performance (5.1%, Russakovsky et al.) on this visual recognition challenge.
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            Automatic coronary artery calcium scoring in cardiac CT angiography using paired convolutional neural networks

            The amount of coronary artery calcification (CAC) is a strong and independent predictor of cardiovascular events. CAC is clinically quantified in cardiac calcium scoring CT (CSCT), but it has been shown that cardiac CT angiography (CCTA) may also be used for this purpose. We present a method for automatic CAC quantification in CCTA. This method uses supervised learning to directly identify and quantify CAC without a need for coronary artery extraction commonly used in existing methods. The study included cardiac CT exams of 250 patients for whom both a CCTA and a CSCT scan were available. To restrict the volume-of-interest for analysis, a bounding box around the heart is automatically determined. The bounding box detection algorithm employs a combination of three ConvNets, where each detects the heart in a different orthogonal plane (axial, sagittal, coronal). These ConvNets were trained using 50 cardiac CT exams. In the remaining 200 exams, a reference standard for CAC was defined in CSCT and CCTA. Out of these, 100 CCTA scans were used for training, and the remaining 100 for evaluation of a voxel classification method for CAC identification. The method uses ConvPairs, pairs of convolutional neural networks (ConvNets). The first ConvNet in a pair identifies voxels likely to be CAC, thereby discarding the majority of non-CAC-like voxels such as lung and fatty tissue. The identified CAC-like voxels are further classified by the second ConvNet in the pair, which distinguishes between CAC and CAC-like negatives. Given the different task of each ConvNet, they share their architecture, but not their weights. Input patches are either 2.5D or 3D. The ConvNets are purely convolutional, i.e. no pooling layers are present and fully connected layers are implemented as convolutions, thereby allowing efficient voxel classification. The performance of individual 2.5D and 3D ConvPairs with input sizes of 15 and 25 voxels, as well as the performance of ensembles of these ConvPairs, were evaluated by a comparison with reference annotations in CCTA and CSCT. In all cases, ensembles of ConvPairs outperformed their individual members. The best performing individual ConvPair detected 72% of lesions in the test set, with on average 0.85 false positive (FP) errors per scan. The best performing ensemble combined all ConvPairs and obtained a sensitivity of 71% at 0.48 FP errors per scan. For this ensemble, agreement with the reference mass score in CSCT was excellent (ICC 0.944 [0.918-0.962]). Aditionally, based on the Agatston score in CCTA, this ensemble assigned 83% of patients to the same cardiovascular risk category as reference CSCT. In conclusion, CAC can be accurately automatically identified and quantified in CCTA using the proposed pattern recognition method. This might obviate the need to acquire a dedicated CSCT scan for CAC scoring, which is regularly acquired prior to a CCTA, and thus reduce the CT radiation dose received by patients.
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              Deep Convolutional Neural Networks for large-scale speech tasks.

              Convolutional Neural Networks (CNNs) are an alternative type of neural network that can be used to reduce spectral variations and model spectral correlations which exist in signals. Since speech signals exhibit both of these properties, we hypothesize that CNNs are a more effective model for speech compared to Deep Neural Networks (DNNs). In this paper, we explore applying CNNs to large vocabulary continuous speech recognition (LVCSR) tasks. First, we determine the appropriate architecture to make CNNs effective compared to DNNs for LVCSR tasks. Specifically, we focus on how many convolutional layers are needed, what is an appropriate number of hidden units, what is the best pooling strategy. Second, investigate how to incorporate speaker-adapted features, which cannot directly be modeled by CNNs as they do not obey locality in frequency, into the CNN framework. Third, given the importance of sequence training for speech tasks, we introduce a strategy to use ReLU+dropout during Hessian-free sequence training of CNNs. Experiments on 3 LVCSR tasks indicate that a CNN with the proposed speaker-adapted and ReLU+dropout ideas allow for a 12%-14% relative improvement in WER over a strong DNN system, achieving state-of-the art results in these 3 tasks.
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                Author and article information

                Journal
                IEEE Transactions on Medical Imaging
                IEEE Trans. Med. Imaging
                Institute of Electrical and Electronics Engineers (IEEE)
                0278-0062
                1558-254X
                January 2018
                January 2018
                : 37
                : 1
                : 81-92
                Article
                10.1109/TMI.2017.2739110
                28809679
                5739be82-79f5-4267-9555-a5e416ab37b8
                © 2018
                History

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