8
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Assessing the feasibility of single target radiosurgery quality assurance with portal dosimetry

      other

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Purpose

          To assess the feasibility of using portal dosimetry ( PD) for pre‐treatment quality assurance of single target, flattening filter free ( FFF), volumetric arc therapy intracranial radiosurgery plans.

          Methods

          A PD algorithm was created for a 10X FFF beam on a Varian Edge linear accelerator (Varian Inc, Palo Alto, CA, USA). Treatment plans that were previously evaluated with Gafchromic EBTXD (Ashland, Bridgewater, NJ, USA) film were measured via PD and analyzed with the ARIA Portal Dosimetry workspace. Absolute dose evaluation for film and PD was done by computing the mean dose in the region receiving greater than or equal to 90% of the max dose and comparing to the mean dose in the same region calculated by the treatment planning system ( TPS). Gamma analysis with 10% threshold and 3%/2 mm passing criteria was performed on film and portal images.

          Results

          Thirty‐six PD verification plans were delivered and analyzed. The average PD to TPS dose was 0.989 ± 0.01 while film to TPS dose was 1.026 ± 0.01. All PD plans passed the gamma analysis with 100% of points having gamma <1. Overall, PD to TPS dose agreement was found to be target size dependent. As target size decreases, PD to TPS dose ratio decreased from 1.004 for targets with diameters between 15–31 mm and 0.978 for targets with diameters less than 15 mm.

          Conclusion

          The agreement of PD to TPS mean dose in the high dose region was found to be dependent on target size. Film measurements did not exhibit size dependence. All PD plans passed the 3%/2 mm gamma analysis, but caution should be used when using PD to assess overall dosimetric accuracy of the treatment plan for small targets.

          Related collections

          Most cited references19

          • Record: found
          • Abstract: found
          • Article: not found

          A technique for the quantitative evaluation of dose distributions.

          The commissioning of a three-dimensional treatment planning system requires comparisons of measured and calculated dose distributions. Techniques have been developed to facilitate quantitative comparisons, including superimposed isodoses, dose-difference, and distance-to-agreement (DTA) distributions. The criterion for acceptable calculation performance is generally defined as a tolerance of the dose and DTA in regions of low and high dose gradients, respectively. The dose difference and DTA distributions complement each other in their useful regions. A composite distribution has recently been developed that presents the dose difference in regions that fail both dose-difference and DTA comparison criteria. Although the composite distribution identifies locations where the calculation fails the preselected criteria, no numerical quality measure is provided for display or analysis. A technique is developed to unify dose distribution comparisons using the acceptance criteria. The measure of acceptability is the multidimensional distance between the measurement and calculation points in both the dose and the physical distance, scaled as a fraction of the acceptance criteria. In a space composed of dose and spatial coordinates, the acceptance criteria form an ellipsoid surface, the major axis scales of which are determined by individual acceptance criteria and the center of which is located at the measurement point in question. When the calculated dose distribution surface passes through the ellipsoid, the calculation passes the acceptance test for the measurement point. The minimum radial distance between the measurement point and the calculation points (expressed as a surface in the dose-distance space) is termed the gamma index. Regions where gamma > 1 correspond to locations where the calculation does not meet the acceptance criteria. The determination of gamma throughout the measured dose distribution provides a presentation that quantitatively indicates the calculation accuracy. Examples of a 6 MV beam penumbra are used to illustrate the gamma index.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Tolerance limits and methodologies for IMRT measurement-based verification QA: Recommendations of AAPM Task Group No. 218.

            Patient-specific IMRT QA measurements are important components of processes designed to identify discrepancies between calculated and delivered radiation doses. Discrepancy tolerance limits are neither well defined nor consistently applied across centers. The AAPM TG-218 report provides a comprehensive review aimed at improving the understanding and consistency of these processes as well as recommendations for methodologies and tolerance limits in patient-specific IMRT QA.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Per-beam, planar IMRT QA passing rates do not predict clinically relevant patient dose errors.

              The purpose of this work is to determine the statistical correlation between per-beam, planar IMRT QA passing rates and several clinically relevant, anatomy-based dose errors for per-patient IMRT QA. The intent is to assess the predictive power of a common conventional IMRT QA performance metric, the Gamma passing rate per beam. Ninety-six unique data sets were created by inducing four types of dose errors in 24 clinical head and neck IMRT plans, each planned with 6 MV Varian 120-leaf MLC linear accelerators using a commercial treatment planning system and step-and-shoot delivery. The error-free beams/plans were used as "simulated measurements" (for generating the IMRT QA dose planes and the anatomy dose metrics) to compare to the corresponding data calculated by the error-induced plans. The degree of the induced errors was tuned to mimic IMRT QA passing rates that are commonly achieved using conventional methods. Analysis of clinical metrics (parotid mean doses, spinal cord max and D1cc, CTV D95, and larynx mean) vs. IMRT QA Gamma analysis (3%/3 mm, 2/2, 1/1) showed that in all cases, there were only weak to moderate correlations (range of Pearson's r-values: -0.295 to 0.653). Moreover, the moderate correlations actually had positive Pearson's r-values (i.e., clinically relevant metric differences increased with increasing IMRT QA passing rate), indicating that some of the largest anatomy-based dose differences occurred in the cases of high IMRT QA passing rates, which may be called "false negatives." The results also show numerous instances of false positives or cases where low IMRT QA passing rates do not imply large errors in anatomy dose metrics. In none of the cases was there correlation consistent with high predictive power of planar IMRT passing rates, i.e., in none of the cases did high IMRT QA Gamma passing rates predict low errors in anatomy dose metrics or vice versa. There is a lack of correlation between conventional IMRT QA performance metrics (Gamma passing rates) and dose errors in anatomic regions-of-interest. The most common acceptance criteria and published actions levels therefore have insufficient, or at least unproven, predictive power for per-patient IMRT QA.
                Bookmark

                Author and article information

                Contributors
                ecovington@uabmc.edu
                Journal
                J Appl Clin Med Phys
                J Appl Clin Med Phys
                10.1002/(ISSN)1526-9914
                ACM2
                Journal of Applied Clinical Medical Physics
                John Wiley and Sons Inc. (Hoboken )
                1526-9914
                01 April 2019
                May 2019
                : 20
                : 5 ( doiID: 10.1002/acm2.2019.20.issue-5 )
                : 135-140
                Affiliations
                [ 1 ] Department of Radiation Oncology University of Alabama – Birmingham South Birmingham AL USA
                Author notes
                [*] [* ] Author to whom correspondence should be addressed. Elizabeth L. Covington

                E‐mail: ecovington@ 123456uabmc.edu .

                Article
                ACM212578
                10.1002/acm2.12578
                6522988
                30933414
                56b7227a-2342-4ad6-8be7-c5d70a0786e3
                © 2019 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 20 August 2018
                : 19 December 2018
                : 11 March 2019
                Page count
                Figures: 4, Tables: 1, Pages: 6, Words: 3841
                Categories
                Technical Note
                Technical Note
                Custom metadata
                2.0
                acm212578
                May 2019
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.6.3 mode:remove_FC converted:16.05.2019

                portal dosimetry,quality assurance,stereotactic radiosurgery

                Comments

                Comment on this article