There is an error in the caption for Fig 1. Please see the complete, correct Fig 1
caption here.
10.1371/journal.pone.0213664.g001
Fig 1
Flowchart displaying the various criteria applied to the initial database to obtain
the final number of hospital records available for the analysis.
SVD = spontaneous vaginal deliveries; IVD = instrumental vaginal deliveries; CS =
cesarean sections.
There is an error in the caption for Fig 2. Please see the complete, correct Fig 2
caption here.
10.1371/journal.pone.0213664.g002
Fig 2
Conceptual framework explaining the relationship between various determinants and
length of hospital stay after childbirth (LoS).
There is an error in Table 2. Please see the complete, correct Table 2 here.
10.1371/journal.pone.0213664.t001
Table 2
Distribution of length of stay (LoS) after childbirth by maternal health factors.
Number; mean LoS (M) ± standard deviation (SD); row percentage (row %). NA = Not applicable.
FACTORS
STRATA
ALL BIRTHS
VAGINAL DELIVERY MODE
Number
M ± SD(days)
SPONTANEOUS(N = 75,497)
INSTRUMENTAL(N = 7,281)
LoS >2 days(Row %)
LoS > 3 days(Row %)
Delivery mode
(Missing: 1)
Spontaneous
75,497
2.9 ± 1.1
64.4
Instrumental
7,281
3.3 ± 1.3
32.0
Caesarean
26,467
4.7 ± 1.7
Mother Age (years)(Missing: 32)
15–19
1,254
3.4 ± 1.5
72.0
31.5
20–24
9,485
3.3 ± 1.5
68.7
34.7
25–29
23,675
3.3 ± 1.4
65.6
27.8
30–34
38,381
3.3 ± 1.4
63.5
32.5
35–39
28,860
3.4 ± 1.5
62.8
32.6
40–44
7,214
3.6 ± 1.6
62.8
37.9
45+
345
4.3 ± 2.3
74.8
40.0
Hypertension/diabetes
(Missing: 63)
No
106,690
3.3 ± 1.4
64.2
31.8
Yes
2,493
4.5 ± 2.4
74.6
41.8
Villi sample
(Missing: 6)
No
105,993
3.3 ± 1.5
64.3
32.0
Yes
4,247
3.5 ± 1.5
67.5
32.0
Amniocentesis
(Missing: 6)
No
91,986
3.3 ± 1.5
64.2
31.2
Yes
17,254
3.5 ±1.5
65.5
36.6
Fetoscopy
(Missing: 6)
No
108,892
3.3 ± 1.5
64.4
32.0
Yes
348
3.4 ±1.5
66.8
37.9
Number of obstetric checks
(Missing: 1)
<4
20,856
3.5 ± 1.6
65.4
35.3
4–7
65,800
3.3 ± 1.4
66.6
32.3
8+
22,589
3.3 ± 1.5
56.7
28.8
Number of US scans in pregnancy
(Missing: 7)
<4
19,003
3.1 ± 1.4
56.5
25.7
4–5
52,873
3.3 ± 1.4
62.6
28.6
6+
37,363
3.6 ± 1.6
72.1
36.9
Labour analgesia
(Missing: 184)
No
89,536
3.3 ± 1.5
63.6
28.5
Yes
19,526
3.3 ± 1.4
67.7
38.1
Labour induction
(Missing: 68)
No
81,859
2.9 ± 1.1
64.1
31.0
Yes
27,319
4.6 ± 1.7
82.6
51.5
Neonatal status
Liveborn
108,944
3.4 ± 1.5
64.5
32.1
Stillborn
302
2.8 ± 2.8
12.3
6.7
Pre-delivery LoS (days)(Missing: 594)
<3
103,769
3.3 ± 1.4
64.3
31.8
3–5
3,142
4.1 ± 2.0
68.8
35.6
6+
1,741
5.0 ± 2.9
69.3
45.8
Presentation
(Missing:181)
Cefalic
Spontaneous
75,118
2.9 ± 1.0
64.4
Instrumental
7,248
3.3 ± 1.3
32.0
Breech
Spontaneous
368
3.0 ± 1.4
61.0
Instrumental
27
3.8 ± 1.6
48.2
Shoulder
Spontaneous
0
NA
NA
NA
Instrumental
0
NA
NA
NA
There are errors in Table 5. Please see the correct Table 5 here.
10.1371/journal.pone.0213664.t002
Table 5
Multiple logistic regression analysis.
Outcome: length of hospital stay (LoS) longer than ED benchmarks (2 days for spontaneous
vaginal deliveries; 3 days for instrumental vaginal deliveries). Effect estimates
for hospital and calendar year adjusted for all other factors. Adjusted odds ratios
(aOR*) and population attributable risks (PAR1
$
, PAR2,** PAR3,
$
PAR4**) with 95% confidence intervals (95%CI). NA = Not available; observations =
complete (case analysis) observations.
FACTORS
STRATA
VAGINAL DELIVERY MODE
SPONTANEOUS
INSTRUMENTAL
aOR (95%CI)(LoS >2 vs. ≤ 2)(73,281 observations)
PAR1 (95%CI)
PAR2 (95%CI)
aOR (95%CI)(LoS >3 vs. ≤ 3)(7,050 observations)
PAR3 (95%CI)
PAR4 (95%CI)
HOSPITAL
A
reference
reference
reference
reference
reference
reference
B
89.38 (78.49; 101.78)
+64.5% (+63.4%; +65.6%)
+65.8% (+64.6%; +67.0%)
7.90 (6.38; 9.78)
+44.8% (+41.0%; +48.5%)
+43.2% (+39.4%; +46.9%)
C
4.86 (4.51; 5.23)
+37.5% (+35.9%; +39.0%)
+38.1% (+36.5%; +39.7%)
0.83 (0.59; 1.17)
-0.0% (-5.2%; +4.3)
-0.3% (-4.3%; +3.7.%)
D
26.47 (22.35; 31.46)
+59.0 (+57.5%; +60.6%)
+60.2% (+58.6%; +61.8%)
7.85 (5.08; 12.12)
+44.7% (+35.1%; +53.4%)
+43.0 (+33.0%; +52.1%)
E
8.40 (7.68; 9.19)
+46.7% (+45.1%; +48.2%)
+47.5 (+45.9%; +49.1%)
2.21 (1.67; 2.94)
+16.1% (+10.7%; +21.5%)
+14.5% (+9.5%; +19.4%)
F
2.93 (2.69; 3.20)
+27.4% (+25.6%; +29.3%)
+27.9% (+26.0%; +29.8%)
0.79 (0.58; 1.08)
-1.1% (-5.2%; +3.1%)
-1.0 (-4.3%; +2.8%)
G
0.77 (0.72; 0.83)
-1.0 (-2.2; +1.0%)
-1.0% (-2.1%; +1.0%)
0.72 (0.56; 0.95)
-2.2% (-5.7%; +1.4%)
-1.7 (-4.7%; +1.3%)
H
2.78 (2.61; 2.96)
+26.3% (+24.8; +27.7%)
+26.7% (+25.2%; +28.2%)
1.53 (1.21; 1.94)
+9.0% (+5.0%; +13.0%)
+7.9% (+4.4%; +11.4%)
I
10.42 (9.49; 11.44)
+49.7% (+48.2%; +51.2%)
+50.6% (+49.0%; +52.1%)
2.85 (2.15; 3.78)
+21.5% (+15.8%; +27.1%)
+19.6% (+14.2%; +24.9%)
J
2.39 (2.24; 2.55)
+23.1% (+21.6%; +24.6%)
+23.5% (+22.0%; +25.0%)
2.56 (2.03; 3.23)
+19.2% (+14.8; +23.5%)
+17.3% (+13.4%; +21.3%)
K
10.30 (9.45 11.21)
+49.5% (+48.1%; +51.0)
+50.4% (+48/9%; +51.9%)
2.41 (1.88; 3.10)
+17.9% (+13.2%; +22.5%)
+16.1% (+11.8%; +20.4%)
* Multiple logistic regression model adjusted for: Health care setting and time-frame
factors (hospital and calendar year); Maternal health factors (mother’s age; hypertension/diabetes;
amniocentesis; number of obstetric checks; number of ultrasound scans performed; labour
induction; labour analgesia; neonatal status; presentation; pre-delivery LoS); Child’s
fragility factors (Apgar score at 5 minutes; ICU admission; multiple birth); Child’s
size factors (gestational age; birthweight; placenta weight); Obstetric history factors
(parity; history of caesarean sections); Socio-demographic factors (father’s age;
mother’s nationality; mother’s educational level)
$
Population Attributable Risk 1 (PAR 1) and 3 (PAR 3). Proportional variation of LoS
< ED after childbirth in the ideal scenario each hospital would be performing as hospital
A during calendar year 2015
** Population Attributable Risk 2 (PAR 2) and 4 (PAR4). Proportional variation of
LoS < ED after childbirth in the ideal scenario each hospital would be performing
as hospital A during calendar year 2015. Estimations of PAR2 and PAR4 calculated only
for low risk pregnancies, defined as conditions of the mother and/or the newborn simultaneously
meeting all the following criteria: for spontaneous vaginal deliveries (PAR 2): mother’s
age<35; no resuscitation performed; child not admitted to ICU; singleton birth; Apgar
score at 1 minute ≥7; Apgar score at 5 minutes ≥8; no labour induction; no women affected
by hypertension/diabetes; birthweight: 2,500–3,999gr; gestational age: 37–40 weeks;
pre delivery LoS <2 days; for instrumental vaginal deliveries (PAR 4): in addition
to all above criteria, the calculation of PAR4 was restricted to women not administered
with labour analgesia.
In the Results, there is an error in the second sentence of the penultimate paragraph.
The correct sentence is: The proportional increase in LoS<ED for SVD would range from
+23.1% (centre J) up to +64.5% (centre B), and would be +59.0%, +49.7%, +49.5%, +46.7%,
+37.5%, +27.4% and +26.3% for centres D, I, K, E, C, F and H respectively (PAR1).
In the Generalizability subsection of the Discussion, there is an error in the first
sentence of the first paragraph. The correct sentence is: The pooled mean LoS for
SVD was 2.9 days in FVG during the whole study period (2005–2015), shorter than the
average figures most recently reported for the whole of Italy (3.4 days).
There are errors in the Methods.
The title of the subsection “Child’s clinical factors fragility” is incorrect. The
correct subsection title is: “Child’s clinical factors.”
In the Statistical analysis subsection, there is an error in the third item of the
first list. The correct third item is: previous spontaneous abortions, as the relative
effect size was not consistent across the two vaginal delivery modes.
In the Maternal health factors subsection, there is an error in the first sentence
of the first paragraph. The correct sentence is: Table 2 displays the classes of clinical
explanatory factors related with the maternal health domain: mother’s age, hypertension/diabetes,
amniocentesis, villi sample, fetoscopy, pre-delivery LoS, presentation, labour induction,
labour analgesia, neonatal status, number of obstetric checks performed, number of
ultrasound (US) scans performed.