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      Multiregional radiomics features from multiparametric MRI for prediction of MGMT methylation status in glioblastoma multiforme: A multicentre study.

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          Abstract

          To build a reliable radiomics model from multiregional and multiparametric magnetic resonance imaging (MRI) for pretreatment prediction of O6-methylguanine-DNA methyltransferase (MGMT) promotor methylation status in glioblastoma multiforme (GBM).

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          Author and article information

          Journal
          Eur Radiol
          European radiology
          Springer Nature America, Inc
          1432-1084
          0938-7994
          Sep 2018
          : 28
          : 9
          Affiliations
          [1 ] Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
          [2 ] Department of Neurosurgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, China.
          [3 ] Department of Radiology, The 3rd Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
          [4 ] Department of Neurosurgery/Neuro-oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China. chenyinsh@sysucc.org.cn.
          [5 ] Department of Neurosurgery, The 3rd Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. lcfjeff@126.com.
          Article
          10.1007/s00330-017-5302-1
          10.1007/s00330-017-5302-1
          29564594
          5510a51a-6b31-4100-8077-054b0301db04
          History

          Radiomics,MGMT methylation,Imaging genomics,Imaging biomarker,Glioblastoma multiforme

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