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      Antihypertensive medication adherence and cardiovascular disease risk: A longitudinal cohort study.

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          Abstract

          Few studies estimated the impact of antihypertensive adherence on cardiovascular diseases (CVD) in a longitudinal cohort with presence of time-dependent confounders. This study aims to assess the association between antihypertensive adherence and CVD using marginal structural Cox model (MSM-Cox) and to characterize blood pressure (BP) trajectories of patients with different adherence.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Atherosclerosis
          Title: Atherosclerosis
          Publisher: Elsevier BV
          ISSN (Electronic): 1879-1484
          ISSN (Print): 0021-9150
          Publication date (Electronic): Mar 2021
          Volume: 320
          Affiliations
          [1 ] Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China; Healthcare Big Data Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
          [2 ] Qingdao Huangdao District Center for Disease Control and Prevention, Qingdao, 266400, Shandong, China.
          [3 ] Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China; Healthcare Big Data Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China. Electronic address: xuefzh@sdu.edu.cn.
          Article
          Publisher Item ID: S0021-9150(21)00005-8
          DOI: 10.1016/j.atherosclerosis.2021.01.005
          PubMed ID: 33516044
          SO-VID: 53c311cd-0398-419a-ba2d-4f5b03f09e24
          History

          Keywords: Hypertension,Cardiovascular disease,MSM-Cox model,Medication adherence,Time-dependent confounder
          Data availability:
          Keywords: Hypertension, Cardiovascular disease, MSM-Cox model, Medication adherence, Time-dependent confounder

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