- Record: found
- Abstract: not found
- Article: not found
Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells
Na Wang ,
De-yu Guo ,
Xiong Tian ,
Hao-peng Lin ,
Yun-pan Li ,
Shao-jun Chen ,
Yu-cai Fu ,
Wen-can Xu ,
Chi-ju Wei
October 2016
October 2016
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
<p class="first" id="d3347214e150">We previously found niacin receptor GPR109A was
expressed in murine islet beta-cells,
and signaling through GPR109A inhibited glucose stimulated insulin secretion (GSIS).
However, the expression of GPR109A in human islets and its functional relevance is
still not known.
</p>