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      The Importance of Sleep for People With Chronic Pain: Current Insights and Evidence

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          ABSTRACT

          We are currently in the midst of a sleep crisis. Our current work and lifestyle environments are normalizing poor sleep with substantial negative impact on our health. Research on sleep has linked sleep deprivation to poorer mental health, obesity, cancer, diabetes, heart disease, and a myriad of other health conditions. Sleep deprivation is an even greater issues for people with musculoskeletal conditions and chronic pain. Between 67% and 88% of individuals with chronic pain experience sleep disruption and insomnia, and at least 50% of people with insomnia report chronic pain. The link between sleep and pain is well documented. Experimental, cohort, and longitudinal studies have all demonstrated that restricted sleep is linked to greater pain. Poor sleep therefore not only affects general health but has a direct impact on inflammation, pain response, and experience. Improving sleep in people living with musculoskeletal conditions and with chronic pain has the potential to deliver great benefit to many. This article describes the evidence base that can underpin such work, including research about the link between pain and sleep as well as theories and approaches to intervention that may help. © 2022 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.

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          Self-determination theory: A macrotheory of human motivation, development, and health.

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            Quantity and Quality of Sleep and Incidence of Type 2 Diabetes

            OBJECTIVE To assess the relationship between habitual sleep disturbances and the incidence of type 2 diabetes and to obtain an estimate of the risk. RESEARCH DESIGN AND METHODS We conducted a systematic search of publications using MEDLINE (1955–April 2009), EMBASE, and the Cochrane Library and manual searches without language restrictions. We included studies if they were prospective with follow-up >3 years and had an assessment of sleep disturbances at baseline and incidence of type 2 diabetes. We recorded several characteristics for each study. We extracted quantity and quality of sleep, how they were assessed, and incident cases defined with different validated methods. We extracted relative risks (RRs) and 95% CI and pooled them using random-effects models. We performed sensitivity analysis and assessed heterogeneity and publication bias. RESULTS We included 10 studies (13 independent cohort samples; 107,756 male and female participants, follow-up range 4.2–32 years, and 3,586 incident cases of type 2 diabetes). In pooled analyses, quantity and quality of sleep predicted the risk of development of type 2 diabetes. For short duration of sleep (≤5–6 h/night), the RR was 1.28 (95% CI 1.03–1.60, P = 0.024, heterogeneity P = 0.015); for long duration of sleep (>8–9 h/night), the RR was 1.48 (1.13–1.96, P = 0.005); for difficulty in initiating sleep, the RR was 1.57 (1.25–1.97, P < 0.0001); and for difficulty in maintaining sleep, the RR was 1.84 (1.39–2.43, P < 0.0001). CONCLUSIONS Quantity and quality of sleep consistently and significantly predict the risk of the development of type 2 diabetes. The mechanisms underlying this relation may differ between short and long sleepers.
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              Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation.

              Sleep disturbance is associated with inflammatory disease risk and all-cause mortality. Here, we assess global evidence linking sleep disturbance, sleep duration, and inflammation in adult humans.
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                Author and article information

                Contributors
                katie.whale@bristol.ac.uk
                Journal
                JBMR Plus
                JBMR Plus
                10.1002/(ISSN)2473-4039
                JBM4
                JBMR Plus
                John Wiley & Sons, Inc. (Hoboken, USA )
                2473-4039
                17 June 2022
                July 2022
                : 6
                : 7 ( doiID: 10.1002/jbm4.v6.7 )
                : e10658
                Affiliations
                [ 1 ] Bristol Medical School University of Bristol Bristol UK
                [ 2 ] National Institute for Health Research Bristol Biomedical Research Centre University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol Bristol UK
                Author notes
                [*] [* ]Address correspondence to: Katie Whale, DHealthPsy, Musculoskeletal Research Unit, Level 1 Learning and Research Building, Southmead Hospital, Bristol, BS10 5NB, UK. E‐mail: katie.whale@ 123456bristol.ac.uk
                Author information
                https://orcid.org/0000-0002-0012-7103
                Article
                JBM410658
                10.1002/jbm4.10658
                9289983
                35866153
                51d6cd17-e69e-4ecd-8384-4f03e743899d
                © 2022 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 14 April 2022
                : 08 April 2022
                : 19 April 2022
                Page count
                Figures: 0, Tables: 0, Pages: 5, Words: 4882
                Funding
                Funded by: NIHR Bristol Biomedical Research Centre , doi 10.13039/100015250;
                Funded by: Department of Health , doi 10.13039/501100003921;
                Funded by: National Institute for Health Research , doi 10.13039/501100000272;
                Funded by: University of Bristol , doi 10.13039/501100000883;
                Funded by: University Hospitals , doi 10.13039/100012324;
                Funded by: Biomedical Research Centre , doi 10.13039/100014461;
                Funded by: National Institute for Health Research , doi 10.13039/501100000272;
                Categories
                Review
                Review
                Custom metadata
                2.0
                July 2022
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.1.7 mode:remove_FC converted:18.07.2022

                practice/policy‐related issues,diseases and disorders of/related to bone,epidemiology,orthopaedics

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